Drug Allergy Testing. (2017)

• Record Type: Book
• Further Information: Note: David Khan, Aleena Banerji.
• Authors: Khan, David; Banerji, Aleena
• Contents: Front Cover; Drug Allergy Testing; Drug Allergy Testing; Copyright; List of Contributors; Preface: Drug Allergy Testing; Contents; 1 -- Epidemiology of Drug Allergy; DRUG HYPERSENSITIVITY REACTIONS; SEVERE CUTANEOUS ADVERSE REACTIONS; ANAPHYLAXIS; PEDIATRIC DRUG ALLERGY; LIMITATIONS IN DIAGNOSIS; RISK FACTORS; GENETICS; CONCLUSIONS; REFERENCES; 2 -- Economic Impact of Drug Allergy; INTRODUCTION; COST OF ADVERSE DRUG REACTIONS, ADVERSE DRUG EVENTS, AND HYPERSENSITIVITY REACTIONS; Cost of Adverse Drug Events and Adverse Drug Reactions; Cost of Hypersensitivity Reactions COSTS OF OVERREPORTING ALLERGIESCOST-EFFECTIVENESS ANALYSES IN DRUG HYPERSENSITIVITY; Genetic Screening in Drug Hypersensitivity; Aspirin Desensitization; SUMMARY; REFERENCES; 3 -- Drug Allergy: Definitions and Phenotypes; DEFINITIONS; PHENOTYPING OF DRUG HYPERSENSITIVITY REACTIONS BY CHRONOLOGY; PHENOTYPING OF DRUG HYPERSENSITIVITY REACTIONS BY CLINICAL MANIFESTATIONS; Clinical Phenotypes Often Associated With Immediate (Acute) Drug Hypersensitivity Reactions and typical elicitors; Urticaria and angioedema; Anaphylaxis; Maculopapular exanthem Symmetric drug-related intertriginous and flexural exanthemAcute generalized exanthematous pustulosis; Bullous exanthems; Drug reaction with eosinophilia and systemic symptoms; Fixed drug eruption; Vasculitis; Organ-specific and miscellaneous drug reactions; Drug-induced autoimmune disease; REFERENCES; 4 -- Immune Mechanisms of Drug Allergy; INTRODUCTION; Gell-Coombs Classification of Immune-Mediated Adverse Drug Reactions; THE IMMUNOPATHOGENESIS OF T CELLâ#x80;#x93;MEDIATED DRUG HYPERSENSITIVITY SYNDROME: ESTABLISHED MODELS; Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis Drug Reaction With Eosinophilia and Systemic SymptomsDrug-Specific Models: The Aromatic Amine Anticonvulsants; Drug-Specific Models: Allopurinol; Drug-Specific Models: Abacavir Hypersensitivity Syndrome; Unexplained Features of T Cellâ#x80;#x93;Mediated Adverse Drug Reactions; FUTURE RESEARCH AND IMPLICATIONS FOR CLINICAL PRACTICE; ABBREVIATIONS; ACKNOWLEDGMENTS; REFERENCES; 5 -- Pharmacogenomics of Drug Allergy; INTRODUCTION; REACTIONS LACKING IMMUNOLOGIC MEMORY; Reactions With a Pharmacologic Component; Reactions With an Off-Target Pharmacologic and/or Immunologic Component Non-IgE-mediated mast-cell activationAspirin exacerbated respiratory disease; Other NSAID reactions. Cutaneous hypersensitivities to aspirin and other NSAID drugs can be classified as per the European Acade...; Drug-induced thrombocytopenia; Heparin-induced thrombocytopenia. Heparin and related anticoagulants are associated with the development of heparin-induced thro...; REACTIONS INVOLVING IMMUNOLOGIC MEMORY; Immediate/Accelerated Immune-Mediated Reactions; Delayed Immune Reactions; Human leukocyte antigen; PHARMACOGENOMIC SCREENING; ACKNOWLEDGEMENT; REFERENCES 6 -- Cutaneous Reactions to Drugs
• Publisher Details: Place of publication not identified : Elsevier
• Publication Date: 2017
• Extent: 1 online resource (250 pages)
• Subjects: 616.97/58; Drug allergy -- Diagnosis; HEALTH & FITNESS / Diseases / General; MEDICAL / Clinical Medicine; MEDICAL / Diseases; MEDICAL / Evidence-Based Medicine; MEDICAL / Internal Medicine; Electronic books
• Languages: English
• ISBNs: 9780323497077; 0323497071
• Related ISBNs: 9780323485517; 0323485510
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.