Targeted therapies in oncology. (2014)

• Record Type: Book
• Further Information: Note: Edited by Giuseppe Giaccone and Jean-Charles Soria.
• Other Names: Giaccone, Giuseppe; Soria, Jean-Charles
• Contents: The role of next generation sequencing technologies / Siddhartha Devarakonda, Daniel Morgensztern and Ramaswamy Govindan -- Signal transduction inhibitors of the HER family / Christina Brzezniak [and others] -- HER-2 inhibition and clinical achievements / Berta Sousa, J. Ribeiro and Fatima Cardoso -- Inhibiting the phosphoinositide 3-kinase/akt/mammaliantarget of rapamycin pathway / Simona Wagner and Janet E. Dancey -- BRAF and MEK inhibitors / Lidia Robert and Antoni Ribas -- KIT and KIT inhibitors / Jean-Yves Blay [and others] -- Targeting the fibroblast growth factor receptor (FGFR) pathway in human cancer / Maria Vittoria Dieci and Fabrice Andre -- Anaplastic lymphoma kinase (ALK) / Aparna Rao and Benjamin Solomon -- MET inhibitors / Apoorva Chawla, Ravi Salgia and Victoria M. Villaflor -- Targeting stem cells / Marcello Maugeri-Saccà and Ruggero De Maria -- The cancer super-chaperone Hsp90 : its posttranslational regulation and drug targeting / Annerleim Walton-Diaz [and others] -- Targeting apoptosis pathways / Pamela M. Holland, David Reese, and Jeffrey Wiezorek -- Targeting angiogenesis / Sophie Postel-Vinay and Jean-Pierre Armand -- Anti-vascular agents / Gianluca Del Conte and Cristiana Sessa -- Immunotherapy : monoclonal antibodies / Patrick M. Forde and Julie R. Brahmer -- Vaccine therapy and integration with other modalities / Benedetto Farsaci [and others] -- Histone deacetylase inhibitors as targeted therapies / Alexandra Zimmer [and others] -- Compounds, targeting androgen pathways / Aurelius Omlin, Carmel Pezaro, and Johann de Bono -- Targeting DNA repair : PARP and Chk1 inhibitors / Peter Stephens and Ruth Plummer -- Inhibitors targeting mitosis / Dan L. Sackett, Edina Komlodi-Pasztor, and Tito Fojo.
• Publisher Details: Boca Raton : CRC Press, Taylor & Francis Group
• Publication Date: 2014
• Extent: 1 online resource (pages)
• Subjects: 616.99/406; Cancer -- Treatment; Neoplasms -- therapy; Genetic Therapy; Immunotherapy; Molecular Targeted Therapy; HEALTH & FITNESS -- Diseases -- General; MEDICAL -- Clinical Medicine; MEDICAL -- Diseases; MEDICAL -- Evidence-Based Medicine; MEDICAL -- Internal Medicine; Cancer -- Treatment; Electronic books
• Languages: English
• ISBNs: 9781842145463; 1842145460
• Related ISBNs: 9781842145456; 1842145452
• Notes: Note: Includes bibliographical references and index.; Note: Print version record.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.