Quantitation and mass spectrometric data of drugs and isotopically labeled analogs. (©2010)
- Record Type:
- Book
- Title:
- Quantitation and mass spectrometric data of drugs and isotopically labeled analogs. (©2010)
- Main Title:
- Quantitation and mass spectrometric data of drugs and isotopically labeled analogs
- Further Information:
- Note: Ray H. Liu, Sheng-Meng Wang, Dennis V. Canfield ; with the assistance of Meng-Yan Wu [and others].
- Other Names:
- Liu, Ray H
Wang, Sheng-Meng
Canfield, Dennis V, 1943- - Contents:
- Part One. Isotopically Labeled Analog as Internal Standard for Drug Quantitation — Methodology Quantitation of Drug in Biological Specimen — Isotopically Labeled Analog of the Analyte as Internal Standard Introduction Significance of Accurate Quantitation Preferred Calibration Method Internal Standard and Quantitation Ions Inadequate Isotopic Purity — An Extrinsic Factor Cross-Contribution Derived from Ion Fragmentation Mechanism — An Intrinsic Factor Fitting Calibration Data 2 H- Versus 13 C-Analogs as Internal Standards Concluding Remarks References Isotopically Labeled Analog of the Analyte as Internal Standard for Drug Quantitation — Chemical Derivatization and Data Collection and Evaluation Introduction Chemical Derivatization Production of Most Favorable Ion-Pairs for Drug Quantitation Exemplar Studies Isotopically Labeled Analogs and Chemical Derivatization Groups Ion Intensity Cross-Contribution Data Full-Scan Mass Spectra Selected Ion Monitoring and Calculation of Cross-Contribution Data: Direct Measurement, Normalized Direct Measurement, Internal Standard Method, Standard Addition Method Assessing the Accuracy of Empirically Determined Cross-Contribution Data: Experimentally Observed Concentration, Theoretically Calculated Concentration, Comparing Empirically Derived and Theoretically Calculated Concentrations — Graphic Presentation, Summary Compilation of Full-Scan Mass Spectra and Ion Intensity Cross-Contribution Tables: Derivatization Procedures,Part One. Isotopically Labeled Analog as Internal Standard for Drug Quantitation — Methodology Quantitation of Drug in Biological Specimen — Isotopically Labeled Analog of the Analyte as Internal Standard Introduction Significance of Accurate Quantitation Preferred Calibration Method Internal Standard and Quantitation Ions Inadequate Isotopic Purity — An Extrinsic Factor Cross-Contribution Derived from Ion Fragmentation Mechanism — An Intrinsic Factor Fitting Calibration Data 2 H- Versus 13 C-Analogs as Internal Standards Concluding Remarks References Isotopically Labeled Analog of the Analyte as Internal Standard for Drug Quantitation — Chemical Derivatization and Data Collection and Evaluation Introduction Chemical Derivatization Production of Most Favorable Ion-Pairs for Drug Quantitation Exemplar Studies Isotopically Labeled Analogs and Chemical Derivatization Groups Ion Intensity Cross-Contribution Data Full-Scan Mass Spectra Selected Ion Monitoring and Calculation of Cross-Contribution Data: Direct Measurement, Normalized Direct Measurement, Internal Standard Method, Standard Addition Method Assessing the Accuracy of Empirically Determined Cross-Contribution Data: Experimentally Observed Concentration, Theoretically Calculated Concentration, Comparing Empirically Derived and Theoretically Calculated Concentrations — Graphic Presentation, Summary Compilation of Full-Scan Mass Spectra and Ion Intensity Cross-Contribution Tables: Derivatization Procedures, Instrumentation, and Analytical Parameters Collection of Mass Spectrometric Data Ion Intensity Cross-Contribution Data Concluding Remarks References Part Two. Mass Spectra of Commonly Abused Drugs and Their Isotopically Labelled Analogs in Various Derivatization Forms Table of Contents for Appendix One Stimulants Opioids Hallucinogens Depressants/Hypnotics Antianxiety Agents Antidepressants Others Part Three. Cross-Contributions of Ion Intensity Between Analytes and Their Isotopically Labeled Analogs in Various Derivatization Forms Table of Contents for Appendix Two Stimulants Opioids Hallucinogens Depressants/Hypnotics Antianxiety Agents Antidepressants Others Index … (more)
- Publisher Details:
- Boca Raton : CRC Press
- Publication Date:
- 2010
- Copyright Date:
- 2010
- Extent:
- 1 online resource (xii, 498 pages), illustrations
- Subjects:
- 615/.1901
Drugs -- Analysis
Central nervous system -- Effect of drugs on
Radiolabeling
Mass spectrometry
Pharmaceutical Preparations -- analysis
Central Nervous System Agents -- chemistry
Isotope Labeling
Mass Spectrometry -- methods
Pharmacy
Medicine
MEDICAL -- Drug Guides
MEDICAL -- Pharmacology
MEDICAL -- Pharmacy
MEDICAL -- Nursing -- Pharmacology
Central nervous system -- Effect of drugs on
Drugs -- Analysis
Mass spectrometry
Radiolabeling
Electronic books - Languages:
- English
- ISBNs:
- 9781420094985
- Related ISBNs:
- 142009498X
9781420094978
1420094971 - Notes:
- Note: Includes bibliographical references and index.
Note: Print version record. - Access Rights:
- Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
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- Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.
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- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library HMNTS - ELD.DS.150419
- Ingest File:
- 01_020.xml