Lipoic acid : energy production, antioxidant activity and health effects /: energy production, antioxidant activity and health effects. (©2008)

• Record Type: Book
• Further Information: Note: Edited by Mulchand S. Patel and Lester Packer.
• Other Names: Patel, Mulchand S; Packer, Lester
• Contents: A trail of research on lipoic acid / Lester J. Reed -- Lipoic acid biosynthesis / Natasha M. Nesbitt [and others] -- The search for potent a-lipoic acid derivatives: chemical and pharmacological aspects / Moriya Ben Yakir, Yehoshua Katzhendler, and Shlomo Sasson -- Novel indole lipoic acid derivatives: synthesis and their antioxidant effects / A. Selen Gurkan and Erdem Buyukbingol -- The a-keto acid dehydrogenase complexes and glycine cleavage system: their involvement in pathways of carbohydrate, protein, and fat metabolism / Robert A. Harris [and others] -- Pyruvate dehydrogenase complex regulation and lipoic acid / Lioubov Korotchkina and Mulchand S. Patel -- Role of lipoyl domains in the function and regulation of the mammalian pyruvate dehydrogenase complex / Thomas E. Roche [and others]. Inactivation and inhibition of a-ketoglutarate dehydrogenase: oxidative modulation of lipoic acid / Kenneth M. Humphries, Amy C. Nulton-Persson, and Luke I. Szweda -- Lipoate-protein ligase A: structure and function / Kazuko Fujiwara [and others] -- A review of the stability & preliminary evaluation of the plasma pharmacokinetics of R-lipoic acid & R-dihydrolipoic acid dosage forms in human plasma from healthy volunteers / D.A. Carlson [and others] -- The pharmacokinetics, metabolism and renal excretion of a-lipoic acid and its main metabolites in humans / Jens Teichert and Rainer Preiss -- Modulation of cellular redox and metabolic status by lipoic acid / Derrick Han and Lester Packer -- The redoxin connection of lipoic acid / J.A. Barcena [and others] -- Lipoic acid as an inducer of phase II detoxification enzymes through activation of Nrf2-dependent gene expression / Kate Peterson Shay, Swapna Shenvi, and Tory M. Hagen. Deficiency disorders of components of the PDH complex: E2, BP & E3 deficiencies / Jessie M. Cameron, Mary C. Maj, and Brian H. Robinson -- The relationship between primary biliary cirrhosis and lipoic acid / Carlo Selmi [and others] -- Effects of lipoic acid on insulin action in animal models of insulin resistance / Erik J. Henriksen and Stephan Jacob -- Activation of cytoprotective signaling pathways by alpha-lipoic acid / A.K. Kiemer and B. Diesel -- Selenotrisulfide derivatives of alpha lipoic acid: potential use as a novel topical antioxidant / William T. Self -- Alpha-lipoic acid: a potent mitochondrial nutrient for improving memory deficit, oxidative stress, and mitochondrial dysfunction / Jiankang Liu -- Effects of alpha-lipoic acid on AMP-activated kinase in different tissues: therapeutic implications for the metabolic syndrome / Eun Koh [and others].
• Publisher Details: Boca Raton : CRC Press/Taylor & Francis Group
• Publication Date: 2008
• Copyright Date: 2008
• Extent: 1 online resource (532 pages)
• Subjects: 615/.35; Lipoic acid; Lipoic acid -- Health aspects; Lipoic acid -- Therapeutic use; Thioctic Acid -- metabolism; Thioctic Acid -- pharmacology; Thioctic Acid -- therapeutic use; MEDICAL -- Pharmacology; Lipoic acid; Lipoic acid -- Health aspects; Lipoic acid -- Therapeutic use; Electronic books
• Languages: English
• ISBNs: 9781420045390; 1420045393
• Related ISBNs: 9781420045376; 1420045377
• Notes: Note: Includes bibliographical references and index.; Note: Print version record.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.