Clinical trial data analysis using R. (2010)

• Record Type: Book
• Further Information: Note: By Ding-Geng Chen, Karl E. Peace.
• Other Names: Chen, Ding-Geng; Peace, Karl E, 1941-
• Contents: Introduction to R; What Is R?; Steps on Installing R and Updating R Packages; R for Clinical Trials; A Simple Simulated Clinical Trial; Concluding Remarks Overview of Clinical Trials; Introduction; Phases of Clinical Trials and Objectives; The Clinical Development Plan; Biostatistical Aspects of a Protocol Treatment Comparisons in Clinical Trials; Data from Clinical Trials; Statistical Models for Treatment Comparisons; Data Analysis in R Treatment Comparisons in Clinical Trials with Covariates; Data from Clinical Trials; Statistical Models Incorporating Covariates; Data Analysis in R Analysis of Clinical Trials with Time-to-Event Endpoints; Clinical Trials with Time-to-Event Data; Statistical Models; Statistical Methods for Right-Censored Data; Statistical Methods for Interval-Censored Data; Step-by-Step Implementations in R Analysis of Data from Longitudinal Clinical Trials; Clinical Trials; Statistical Models; Analysis of Data from Longitudinal Clinical Trials Sample Size Determination and Power Calculation in Clinical Trials; Prerequisites for Sample Size Determination; Comparison of Two Treatment Groups with Continuous Endpoints; Two Binomial Proportions; Time-to-Event Endpoint; Design of Group Sequential Trials; Longitudinal Trials; Relative Changes and Coefficient of Variation: An Extra Meta-Analysis of Clinical Trials; Data from Clinical Trials; Statistical Models for Meta-Analysis; Meta-Analysis of Data in R Bayesian Analysis Methods in Clinical Trials; Bayesian Models; R Packages in Bayesian Modeling; MCMC Simulations; Bayesian Data Analysis Analysis of Bioequivalence Clinical Trials ; Data from Bioequivalence Clinical Trials; Bioequivalence Clinical Trial Endpoints; Statistical Methods to Analyze Bioequivalence; Step-by-Step Implementation in R Analysis of Adverse Events in Clinical Trials; Adverse Event Data from a Clinical Trial; Statistical Methods; Step-by-Step Implementation in R Analysis of DNA Microarrays in Clinical Trials; DNA Microarray; Breast Cancer Data Bibliography Index Concluding Remarks appear at the end of each chapter.
• Publisher Details: Place of publication not identified : CRC Press
• Publication Date: 2010
• Extent: 1 online resource (387 pages), (61 illustrations)
• Subjects: 615.580724; Drugs -- Testing -- Statistical methods; Clinical trials -- Statistical methods; R (Computer program language)
• Languages: English
• ISBNs: 9781439840214; 1439840210
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.