Freeze drying/lyophilization of pharmaceutical and biological products. (2010)

• Record Type: Book
• Further Information: Note: Edited by Louis Rey, Joan C. May.
• Other Names: Rey, Louis; May, Joan C (Joan Christine)
• Contents: Glimpses into the realm of freeze-drying : classical issues and new ventures / Louis Rey -- Structural and dynamic properties of bulk and confined water / Marie-Claire Bellissent-Funeland, Jose Teixeira -- Freezing and annealing phenomena in lyophilization / Jim A. Searles -- Phase separation of freeze-dried amorphous solids : the occurrence and detection of multiple amorphous phases in pharmaceutical systems / Adora M. Padilla and Michael J. Pikal -- The use of microscopy, thermal analysis, and impedance measurements to establish critical formulation parameters for freeze-drying cycle development / Kevin R. Ward and Paul Matejtschuk -- The relevance of thermal properties for improving formulation and cycle development : application to freeze-drying of proteins / Stéphanie Passot [and others] -- Freezing-and drying-induced perturbations of protein structure and mechanisms of protein protection by stabilizing additives / John F. Carpenter, Ken-ichi Izutsu, and Theodore W. Randolph -- Mechanisms of protein stabilization during freeze-drying storage : the relative importance of thermodynamic stabilization and glassy state relaxation dynamics / Michael J. Pikal -- Formulation characterization / D.Q. Wang -- Practical aspects of freeze-drying of pharmaceutical and biological products using nonaqueous cosolvent systems / Dirk L. Teagarden, Wei Wang, and David S. Baker -- Regulatory control of freeze-dried products : importance and evaluation of residual moisture / Joan C. May -- Freeze-drying of biological standards / Paul Matejtschuk, Michelle Stanley, and Paul Jefferson -- Molecular mobility of freeze-dried formulations as determined by NMR relaxation times, and its effecton storage stability / Sumie Yoshioka and Yukio Aso -- Scanning electron microscopy : a powerful tool for imaging freeze-dried material / Tauno Jalanti -- Pharmaceutical packaging for lyophilization applications / Claudia Dietrich [and others] -- Closure and container considerations in lyophilization / Fran L. DeGrazio -- Extractables and leachables as container closure considerations in lyophilization / Diane Paskiet and Fran L. DeGrazio -- Optimizing the throughput of freeze-dryers within a constrained design space / Jim A. Searles -- Monitoring and control of industrial freeze-drying operations : the challenge of implementing quality-by-design (QbD) / Miquel Galan -- Process analytical technology in industrial freeze-drying / Antonello A. Barresi, Davide Fissore, and Daniele L. Marchisio -- Practical considerations for freeze-drying in dual chamber package systems / Dirk L. Teagarden [and others] -- Lyophilization and irradiation as an integrated process / Dalal Aoude-Werner and Florent Kuntz.
• Edition: 3rd ed
• Publisher Details: New York : Informa Healthcare
• Publication Date: 2010
• Extent: 1 online resource (564 pages), illustrations
• Subjects: 615/.19; Freeze-drying; Drugs -- Drying; Biological products -- Drying; Freeze Drying -- methods; Biological Agents; Pharmaceutical Preparations; MEDICAL -- Drug Guides; MEDICAL -- Pharmacology; MEDICAL -- Pharmacy; MEDICAL -- Nursing -- Pharmacology; Biological products -- Drying; Drugs -- Drying; Freeze-drying; Electronic books
• Languages: English
• ISBNs: 9781439825761; 1439825769
• Related ISBNs: 9781439825754; 1439825750
• Notes: Note: Includes bibliographical references and index.; Note: Print version record.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.