Quantitative understanding of biosystems : an introduction to biophysics /: an introduction to biophysics. (2011)

• Record Type: Book
• Further Information: Note: Thomas M. Nordlund.
• Other Names: Nordlund, Thomas M
• Contents: INTRODUCTION, APPROACH, AND TOOLS; Introduction to a New World ; Biological and Nonliving Worlds Contrasted; Hierarchical Structure and Function; Some Important Quantities to Get Started; Biophysics and Biochemistry Operate in Water (Water 1); Important or "Hot" Issues in Biophysics, or How to Be Out-of-Date Quickly; Is There a Career Here Somewhere?; Read Appendix A How (Most) Physicists Approach Biophysics; Dealing with Nonspherical Cows: Drive for Simplicity; Two Approaches to Biosystems; Comparison of "Physics" and "Biology" Approaches to Organisms; Memorization: Its Advantages and Dangers Math Tools: First Pass; What Math Do We Need?; Notation: Mathematics vs. Physics Notations; Approximations; Vectors; Two- and Three-Dimensional Geometry; Calculus; Differential Equations; Distributions STRUCTURE AND FUNCTION; Water; Introduction; Structure; Unusual Physical Properties; Summary of Important Physical Properties; Bulk vs. Local Structures; Diffusion and Chemical Reactions in Water; Solutes and the Solvent Power of Water; Points to Remember Structures: From 0.1 to 10 nm and Larger; Software to Display and Analyze Biological Structures; Solvents; Small Molecules; Medium-Sized Molecules: Components of Large Biomolecules; Forces and Free Energies; Biopolymers; Macromolecules: When Does a Molecule Become a Macroscopic Object?; Points to Remember First Pass at Supramolecular Structures: Assemblies of Biomolecules; Measuring Properties of Three-Dimensional Aggregates; Small Aggregates; Large Aggregates; Two-Dimensional Aggregates: Membranes; Points to Remember Putting a Cell Together: Physical Sketch; Minimal, Prokaryotic, and Eukaryotic Cells; Physiology: Selective Overview; Reproduction, DNA, and the Cell Nucleus; Sensors and Recognition: Responding to the Outside World without Eyes BIOLOGICAL ACTIVITY: QUANTUM MICROWORLD; Quantum Primer; Quantum Glossary; Schrödinger Equation and Other Tools of Quantum Mechanics; Pauli Exclusion Principle; From Atoms to Molecules; Collisions of Atoms and Molecules; Classical vs. Quantum: Is a 1-mm-Long Molecule of DNA a Quantum Object?; Points to Remember Light and Life; Light: Our Energy Source; Crucial Differences between One 5-eV and Two 2.5-eV Photons; Properties of Photons; Scattering and Refraction; Absorption Spectra; Emission Spectra; Einstein Relations between Absorption and Emission of Atoms (Graduate Section); Intersystem Crossing: Singlets (S = 0) to Triplets (S = 1); Energy Transfer (FRET); Points to Remember Photosynthesis; Global Numbers; Overall Process; Structural Organization of Photosynthetic Units; Light-Harvesting (Antenna) Proteins: Arrays of Absorbers; Reaction Centers and Charge Separation: Purple Bacteria and Cyanobacteria; Artificial Models and Nonpolluting Energy Production; Points to Remember Direct Ultraviolet Effects on Biological Systems; Types and Sources of UV Light; Divisions of the UV for Health Purposes: UV-A, UV-B, and UV-C; UV Damage to Organisms: "Action Spectra"; Wavelength-Dependent Photochemical Yields and Protein Damage; UV Damage to DNA; Optical Properties of the Skin; Sunscreens; Points to Remember BIOLOGICAL ACTIVITY: (CLASSICAL) MICROWORLD; Mechanics and Dynamics; Conservation Laws, Newton’s Laws, Forces, and Torques; Friction: Familiar and Less Familiar Examples of Motion; Gravitational Forces; Volume Changes and Compressibility; Stress and Strain; Force of Friction, Dissipation, Inertia, and Disorder; Fluids and Turbulence; Points to Remember Random Walks, Diffusion, and Polymer Conformation; Review of Kinetic Theory of Gases: Implications for Biomolecular Averaging; One-Dimensional Random Walk: Probabilities and Distributions; Spreadsheet Model for a One-Dimensional Random Walk; Three-Dimensional Random Walk; Diffusion in the Bulk; Reprise of Photosynthetic Light Harvesting; Biopolymers—A Random Reprise; Points to Remember Statistical Physics and Thermodynamics Primer; Important Quantities: Temperature, Pressure, Density, and Number; Statistical Mechanical View and Distributions; Equipartition of Energy; "Internal" Energy: Kinetic (K) and Potential (U); Heat, Internal Energy, Work, and Enthalpy; Conservative and Nonconservative Forces: DNA Example; Ideal Gas Law; Entropy: Gases and Polymers; Free Energy (Gibbs); Energy Diagrams; Boltzmann Distribution if Numbers Vary: Gibbs Distribution; Equilibrium Constants in Ideal, Uniform Solutions; Free Energy: Enthalpy, Entropy, Mixing, Gradients, Potential, and ATP; Points to Remember Reactions: Physical View; Energy, Entropy, and Free Energy Diagrams; Rate Theory I: Activation-Energy Model; Diffusion-Controlled Rates (Bimolecular); Effects of Temperature on Rate Constants; Quantum Tunneling; A ⇌ B: Unimolecular Reactions; A + B → C Binding Reactions: Free-Solution Reactions; Complex Reactions: Rate-Determining Steps and Michaelis–Menten Analysis; Driving Forces; Reversibility and Detailed Balance; Single-Molecule Behavior; Points to Remember Molecular Machines: Introduction; Basic Considerations for Motors; DNA-Manipulating Motors; Points to Remember Assembly; Overview of Assembly Issues; Kinetics and Equilibrium; Restricted Space for Assembly; Entropic Drive: Ordered Structures Can Be Driven by Random Processes; Nucleosomes and Nucleosome-Like Structures; Points to Remember Appendix A: Reading Skills and Information Sources; Appendix B: Snapshot of the Supporting CD Glossary Further Resources Index Problem Solving and References appear at the end of each chapter.
• Publisher Details: Boca Raton : Taylor & Francis
• Publication Date: 2011
• Extent: 1 online resource (xxii, 557 pages), illustrations (some color)
• Subjects: 571.4; Biophysics -- Textbooks; Biophysics; Electronic books; Textbooks
• Languages: English
• ISBNs: 9781439891131; 1439891133
• Notes: Note: Includes bibliographical references and index.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.