Neurobiology of Huntington's disease : applications to drug discovery /: applications to drug discovery. ([2011])

• Record Type: Book
• Further Information: Note: Edited by Donald C. Lo and Robert E. Hughes.
• Editors: Lo, Donald C; Ph.D, Hughes, Robert E
• Contents: Huntington's disease : clinical features and routes to therapy / Henry L. Paulson and Roger L. Albin -- Huntington's disease pathogenesis : mechanisms and pathways / Albert R. La Spada, Patrick Weydt, and Victor V. Pineda -- Protein interactions and target discovery in HD / John P. Miller and Robert E. Hughes -- Target validation for Huntington's disease / Seung P. Kwak, James K.T. Wang, and David S. Howland -- High-throughput and high-content screening for Huntington's disease therapeutics / Hemant Varma, Donald C. Lo, and Brent R. Stockwell -- Value of invertebrate genetics and biology to develop neuroprotective and preventive medicine in Huntington's disease / Christian Neri -- Mouse models for validating preclinical candidates for HD / X. William Yang and Michelle Gray -- Pharmaceutical development for HD / Richard J. Morse [and others] -- RNA and DNA-based therapies for Huntington's disease / Meghan Sass and Neil Aronin -- Recombinant intrabodies as molecular tools and potential therapeutics for Huntington's disease / Ali Khoshnan [and others] -- Biomarkers to enable the development of neuroprotective therapies for Huntington's disease / Steven M. Hersch and H. Diana Rosas -- Huntington disease : clinical experimental therapeutics / Ray Dorsey and Ira Shoulson.
• Publisher Details: Boca Raton : CRC Press/Taylor & Francis Group
• Publication Date: 2011
• Extent: 1 online resource, illustrations (some color)
• Subjects: 616.851 N494; Huntington's disease -- Pathophysiology; Huntington's disease -- Molecular aspects; Neuropharmacology; Huntington Disease -- physiopathology; Drug Discovery -- methods; Huntington Disease -- drug therapy; HEALTH & FITNESS -- Diseases -- General; MEDICAL -- Clinical Medicine; MEDICAL -- Diseases; MEDICAL -- Evidence-Based Medicine; MEDICAL -- Internal Medicine; Electronic books
• Languages: English
• ISBNs: 9781420008258; 1420008250
• Related ISBNs: 9780849390005; 0849390001
• Notes: Note: Includes bibliographical references and index.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.