Adaptive design methods in clinical trials. (©2012)

• Record Type: Book
• Further Information: Note: Shein-Chung Chow, Mark Chang.
• Other Names: Chow, Shein-Chung, 1955-; Chang, Mark
• Contents: Protocol amendment -- Adaptive randomization -- Adaptive hypotheses -- Adaptive dose-escalation trials -- Adaptive group sequential design -- Statistical tests for adaptive seamless designs -- Adaptive sample size adjustment -- Two-stage adaptive design -- Adaptive treatment switching -- Bayesian approach -- Biomarker adaptive trials -- Target clinical trials -- Sample size and power estimation -- Clinical trial simulation -- Regulatory perspectives : a review of FDA draft guidance.
• Edition: 2nd ed
• Publisher Details: Boca Raton, FL : CRC Press
• Publication Date: 2012
• Copyright Date: 2012
• Extent: 1 online resource (xvi, 358 pages), illustrations
• Subjects: 610.72/4; Clinical trials; Adaptive sampling (Statistics); Experimental design; Clinical trials -- Statistical methods; Clinical Trials as Topic -- methods; Research Design; Biometry -- methods; Models, Statistical; MEDICAL -- Laboratory Medicine; Adaptive sampling (Statistics); Clinical trials; Clinical trials -- Statistical methods; Experimental design; Electronic books
• Languages: English
• ISBNs: 9781439839881; 1439839883
• Related ISBNs: 9781439839874; 1439839875
• Notes: Note: Includes bibliographical references and index.; Note: Print version record.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.