Cardiac electrophysiology : from cell to bedside /: from cell to bedside. ([2014])

• Record Type: Book
• Uniform Title: Cardiac electrophysiology (2014)
• Further Information: Note: [edited by] Douglas P. Zipes, Jose Jalife.
• Editors: Zipes, Douglas P; Jalife, José
• Contents: Structural and molecular bases of ion channel function. Voltage-gated sodium channels and electrical excitability of the heart -- Calcium channels in the heart -- Voltage-regulated potassium channels -- Structural and molecular bases of cardiac inward rectifier potassium channel function -- Mammalian calcium pumps in health and disease -- Structural and molecular bases of sarcoplasmic reticulum ion channel function -- Structural and molecular bases of mitochondrial ion channel function -- Molecular organization, gating, and function of gap junction channels -- Biophysics of cardiac ion channel function. Biophysics of normal and abnormal cardiac sodium channel function -- Regulation of cardiac calcium channels -- KCNQ₁/KCNE₁ macromolecular signaling complex: channel microdomains and human disease -- Structural determinants and biophysical properties of hERG₁ channel gating -- Molecular regulation of cardiac inward rectifier potassium channels by pharmacologic agents -- Cardiac stretch-activated channels and mechano-electric coupling -- Biophysical properties of gap junctions -- Excitation-contraction coupling -- Intermolecular interactions and cardiomyocyte electrical function. Ion channel trafficking in the heart -- Macromolecular complexes and regulation of the sodium channel Nav1.5 -- Calmodulin and CamKII as Ca ² switches for cardiac ion channels -- Macromolecular complexes and cardiac potassium channels -- Reciprocity of cardiac sodium and potassium channels in the control of excitability and arrhythmias -- The intercalated disc: a molecular network that integrates electrical coupling, intercellular adhesion, and cell excitability -- Scaffolding proteins and ion channel diseases -- Epigenetics in cardiac rhythm diseases -- Cell biology of cardiac impulse initiation and propagation. Cardiac impulse is initiated by a coupled system of membrane ion channels and Ca²+ cycling proteins -- Biological pacing -- Intercellular communication and impulse propagation -- Mechanisms of atrioventricular nodal excitability and propagation -- Cell biology of the specialized cardiac conduction system -- Cardiac fibroblasts and arrhythmogenesis -- Models of cardiac excitation. Ionic mechanisms of atrial action potentials -- Models of the ventricular action potential in health and disease -- Calcium signaling in cardiomyocyte models with realistic geometries -- Theory of rotors and arrhythmias -- Supraventricular arrhythmias in a realistic 3D model of the human atria -- Cardiac electromechanical models -- Neural control of cardiac electrical activity. CaV1.2 and [beta]-adrenergic regulation of cardiac function -- Cholinergic and constitutive regulation of atrial potassium channel -- Pulmonary vein ganglia and the neural regulation of the heart rate -- Neural activity and atrial tachyarrhythmias -- Sympathetic innervation, denervation, and cardiac arrhythmias -- Arrhythmia mechanisms. Dominant frequency and the mechanisms of initiation and maintenance of atrial fibrillation -- Rotors in human atrial fibrillation -- Atrial ischemia and fibrillation -- The molecular pathophysiology of atrial fibrillation -- Myofibroblasts, cytokines, and persistent atrial fibrillation -- Role of the autonomic nervous system in atrial fibrillation -- Mechanisms of ventricular tachycardia and fibrillation -- Molecular genetics and pharmacogenomics. Genetics of atrial fibrillation -- Mechanisms in heritable sodium channel diseases -- Inheritable potassium channel disease -- Genetics and cellular mechanisms of the J wave syndromes -- Inheritable phenotypes associated with altered intracellular calcium regulation -- Pharmacologic, genetic and cell therapy of ion channel dysfunction. Pharmacologic bases of antiarrhythmic therapy -- Pharmacogenomics of cardiac arrhythmias -- Optogenetic control of heart muscle -- Cell therapy and regenerative electrophysiology -- Diagnostic evaluation. Assessment of the patient with a cardiac arrhythmia -- Differential diagnosis of narrow and wide complex tachycardias -- Mapping and imaging -- CT and MRI for electrophysiology -- Intracardiac echocardiography for electrophysiology -- Exercise-induced arrhythmias -- Cardiac monitoring: short- and long-term recording -- Electrocardiographic imaging in patients with acute coronary syndrome -- Head-up tilt table testing -- Autonomic testing and cardiac risk -- Monophasic action potential recording -- T wave alternans -- Noninvasive electrocardiographic imaging of human ventricular arrhythmias and electrophysiological substrate -- Genetic testing -- Supraventricular tachyarrhythmias: mechanisms, clinical features, and management. Sinus node abnormalities -- Atrial tachycardia -- Typical and atypical atrial flutter: mapping and ablation -- Atrial fibrillation: paroxysmal, persistent, and permanent -- Preexcitation, atrioventricular reentry, and variants -- Electrophysiological characteristics of atrioventricular nodal reentrant tachycardia -- Atrial tachyarrhythmias in adults with congenital heart disease -- Junctional tachycardia -- Ventricular tachyarrhythmias: mechanisms, clinical features, and management. Premature ventricular complexes -- Outflow tract ventricular tachyarrhythmias: mechanisms, clinical features, and management -- Fascicular ventricular arrhythmias -- Bundle branch reentry tachycardia -- Ischemic heart disease -- Ventricular tachycardia in patients with dilated cardiomyopathy -- Ventricular arrhythmias in hypertrophic cardiomyopathy -- Ventricular tachycardias in arrhythmogenic right ventricular dysplasia/cardiomyopathy -- VTs in catecholaminergic cardiomyopathy (catecholaminergic polymorphic ventricular tachycardia) -- Ventricular arrhythmias in heart failure -- Ventricular tachycardia in noncompaction cardiomyopathy -- Ventricular arrhythmias in Takotsubo cardiomyopathy -- Brugada syndrome 1992-2012: twenty years of scientific progress -- Long and short QT syndromes -- Andersen-Tawil syndrome -- Timothy syndrome -- J wave syndromes -- Idiopathic ventricular fibrillation -- Sudden infant death syndrome -- Sudden cardiac death in adults -- Arrhythmias in patients with neurologic disorders -- Drug-induced ventricular tachycardia -- Syncope and AV block. Syncope -- Postural orthostatic tachycardia syndrome -- Progressive conduction system disease -- Atrioventricular block -- Arrhythmias in special populations. Sex differences in arrhythmias -- Sudden cardiac deaths in athletes, including commotio cordis -- Arrhythmias in pediatric population -- Sleep-disordered breathing and arrhythmias -- Pharmacologic therapy. Standard antiarrhythmic drugs -- New antiarrhythmic drugs and new concepts for old drugs -- Impact of nontraditional antiarrhythmic drugs on sudden cardiac death -- Prevention of stroke in patients with atrial fibrillation -- Electrical therapy. Implantable cardioverter defibrillators: technical aspects -- Implantable cardioverter defibrillator: clinical aspects -- Implantable pacemakers -- Cardiac resynchronization therapy -- Newer applications of pacemakers -- Catheter ablation: technical aspects -- Catheter ablation: clinical aspects -- Ablation for atrial fibrillation -- Ablation of supraventricular tachyarrhythmias -- Catheter ablation for ventricular tachycardia in patients with structural heart disease -- Special ablation approaches: epicardial, other -- Ablation in pediatrics -- Catheter ablation in congenital heart disease -- Surgery for arrhythmias. Surgery for atrial fibrillation and other SVTs -- Surgery for ventricular arrhythmias -- Vagal stimulation for heart failure -- New approaches. Spinal cord stimulation for heart failure and arrhythmias -- Left atrial occluders/isolation.
• Publisher Details: Philadelphia, PA : Elsevier/Saunders
• Publication Date: 2014
• Copyright Date: 2014
• Extent: 1 online resource (xxvi, 1332 pages), illustrations (chiefly color)
• Subjects: 616.1/28; Arrhythmia; Heart -- Electric properties; HEALTH & FITNESS -- Diseases -- General; MEDICAL -- Clinical Medicine; MEDICAL -- Diseases; MEDICAL -- Evidence-Based Medicine; MEDICAL -- Internal Medicine; Arrhythmia; Heart -- Electric properties; Arrhythmia; Electrophysiology; Heart conduction system; Arrhythmias, Cardiac; Electrophysiologic Techniques, Cardiac; Heart -- physiology; Electronic books; Electronic books
• Languages: English
• ISBNs: 9781455770106; 1455770108
• Related ISBNs: 9781455728565; 145572856X
• Notes: Note: Includes bibliographical references and index.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.