High throughput screening methods evolution and refinement /: evolution and refinement. (2016)

• Record Type: Book
• Further Information: Note: Editors: Joshua A. Bittker, Nathan T. Ross.
• Editors: Bittker, Joshua A; Ross, Nathan T
• Contents: Perspective/overview: State of the art in HTS at the academic-industry interface; Assay design and optimization; Assessment of available compound collections; Novel approaches to discovery and analysis of interesting compound combinations; Modern biophysical methods in target-based screening; Genetic perturbation methods; Understanding luminescence-based screens; Measuring interactions in live cells; Approaches to high-content imaging and multi-feature analysis; Profiling of genetically characterized cell systems; Multidimensional profile-based screening; Using biological systems that better recapitulate physiology; Phenotypic screens with model organisms; Encoded libraries; Modern virtual screening; Research data management; Small molecule bioactivity databases; Chemical biology in a pharma environment; Practical aspects of funding and executing high-throughput screens
• Publisher Details: Cambridge, England : Royal Society of Chemistry
• Publication Date: 2016
• Extent: 1 online resource
• Subjects: 615.1/9; SCIENCE / Chemistry / Industrial & Technical; High throughput screening (Drug development); SCIENCE / Life Sciences / Biology; Scientific equipment, experiments & techniques; Biology, life sciences; Electronic books
• Languages: English
• ISBNs: 9781782626770; 1782626778
• Related ISBNs: 1782624716; 9781782624714
• Notes: Note: Print version record.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.