Advances in physical organic chemistry. (2016)

• Record Type: Book
• Further Information: Note: Edited by Ian H. Williams and Nicholas H. Williams.
• Other Names: Williams, Ian H; Williams, Nicholas H
• Contents: Front Cover; Advances in Physical Organic Chemistry; ADVISORY BOARD; Advances in Physical Organic Chemistry; Copyright; Contents; CONTRIBUTORS; PREFACE; One -- Equilibrium Effective Molarity As a Key Concept in Ring-Chain Equilibria, Dynamic Combinatorial Chemistry, Co ... ; 1. INTRODUCTION; 2. EFFECTIVE MOLARITY; 3. EQUILIBRIUM MACROCYLIZATIONS; 3.1 Ring-Chain Equilibria; 3.2 Ring-Ring Equilibria; 3.3 Self-Assembly Macrocyclizations; 4. DYNAMIC COMBINATORIAL CHEMISTRY; 4.1 One-Monomer Dynamic Libraries; 4.1.1 Dynamic Libraries From Transesterification Reaction. 4.1.2 Dynamic Libraries From Olefin Metathesis Reaction4.1.3 Dynamic Libraries From Transacetalation (Formal Metathesis) Reaction; 4.1.4 Dynamic Libraries From Imine Metathesis; 4.1.5 Dynamic Libraries From Hydrogen Bonding Interactions (Supramolecular DLs); 4.2 Two-Monomer Dynamic Libraries; 4.3 Templated Dynamic Libraries; 5. COOPERATIVITY AND SELF-ASSEMBLY; 5.1 Statistical Factors and Microscopic Constants; 5.1.1 The Symmetry Number Method; 5.1.2 The Direct Counting Method; 5.2 Allosteric Cooperativity; 5.3 Chelate Effect and Chelate Cooperativity; 5.4 Interannular Cooperativity. 5.5 Stability of an Assembly6. CONCLUSION; REFERENCES; Two -- Thermodynamic Effective Molarities for Supramolecular Complexes; 1. INTRODUCTION; 1.1 Multivalency and Cooperativity; 1.2 Effective Molarity; 2. EFFECTIVE MOLARITIES FOR SUPRAMOLECULAR COMPLEXES; 2.1 Data Collection; 2.2 Examples of Different Types of Supramolecular Complex; 2.2.1 DMC; 2.2.2 H-Bonding Interactions; 2.2.3 Coordination; 2.2.4 Hydrophobic Effects; 2.2.5 Multiple Binding; 2.2.6 Biomolecules; 2.3 Distribution of Effective Molarity Values; 2.3.1 Relationship Between Association Constants and Values of Effective Molarity. 2.4 Supramolecular Complexes With Very Large Values of Effective Molarity2.5 Supramolecular Complexes With Very Small Values of Effective Molarity; 2.6 Solvent Effects on Effective Molarity; 3. CONCLUSION; APPENDIX: COLLECTION OF THERMODYNAMIC EFFECTIVE MOLARITY VALUES FOR SUPRAMOLECULAR COMPLEXES; ACKNOWLEDGEMENTS; REFERENCES; Three -- Reactivity of Nucleic Acid Radicals; 1. INTRODUCTION; 2. RADICAL FORMATION IN NUCLEIC ACIDS; 3. THE NORRISH TYPE I PHOTOREACTION; 4. C1'-RADICAL GENERATION, REACTIVITY AND RELATED MECHANISTIC IMPLICATIONS; 4.1 C12 Radical Formation; 4.2 C12 Radical Reactivity. 4.3 Utility of C12 Radical Generation as a Source of 2-Deoxyribonolactone in Mechanistic Studies4.4 Probing DNA Repair Enzyme Activity Using Independently Generated 22 Deoxyuridin-12 yl Radical (3); 5. C22 RADICAL GENERATION AND REACTIVITY IN DNA, RIBONUCLEOSIDES AND RNA; 5.1 C22 Radical Formation Following Irradiation of 5-Halopyrimidine Nucleotides in DNA; 5.2 Generation and Reactivity of the 22 Radical in RNA; 5.3 C22 Radical Formation and Reactivity Following Irradiation of 5-Bromouridine in RNA; 6. C32 RADICAL GENERATION AND REACTIVITY IN DNA.
• Publisher Details: Place of publication not identified : Elsevier
• Publication Date: 2016
• Extent: 1 online resource
• Subjects: 547.13; Physical organic chemistry; SCIENCE -- Chemistry -- Organic; Electronic books
• Languages: English
• ISBNs: 0128050810; 9780128050811
• Related ISBNs: 9780128047163; 012804716X
• Notes: Note: Print version record.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.