Micro- and nanotechnology in vaccine development. ([2017])

• Record Type: Book
• Further Information: Note: Edited by Mariusz Skwarczynski, Istvan Toth.
• Editors: Skwarczynski, Mariusz; Toth, Istvan
• Contents: Cover; Title page; Copyright page; Contents; List of Contributors; Introduction; Chapter One -- The Growing Influence of Nanotechnology in Our Lives; 1.1 -- Nanomaterials and Fabrication Techniques; 1.1.1 -- Nanoparticles; 1.1.2 -- Nanowires; 1.1.3 -- Nanofilms; 1.2 -- Nanomaterials in Modern Life; 1.2.1 -- Zero-dimensional nanostructures; 1.2.2 -- One-dimensional nanostructures; 1.2.3 -- Two-dimensional nanostructures; 1.3 -- Conclusions; References; Chapter Two -- Nanotechnology in Medical Research; 2.1 -- Introduction; 2.2 -- Diagnostic Nanoparticles; 2.2.1 -- Imaging agents. 2.2.1.1 -- Contrast Agents for MRI2.2.1.2 -- Contrast Agents for CT; 2.2.1.3 -- PET and SPECT Tracers; 2.2.1.4 -- Optical Imaging Agents; 2.2.1.5 -- Ultrasound Imaging Agents; 2.2.1.6 -- Photoacoustic Contrast Agents; 2.2.2 -- Nanoparticle biosensors; 2.2.2.1 -- Sensing of Biomarkers; 2.2.2.2 -- Sensing of Infectious Diseases; 2.3 -- Therapeutic Nanoparticles; 2.3.1 -- Delivery systems and therapeutics; 2.3.2 -- Drug loading; 2.3.3 -- Targeted nanoparticles; 2.4 -- Multimodal Nanoparticles; 2.4.1 -- Multimodal imaging agents; 2.4.2 -- Theranostics; 2.4.3 -- Personalized multimodal therapy. 2.5 -- In DevelopmentReferences; Chapter Three -- Introduction to Vaccines and Vaccination; 3.1 -- Introduction to Vaccines and Vaccination; 3.1.1 -- A brief history of vaccines and vaccination; 3.1.2 -- The rationale behind vaccination; 3.1.3 -- Vaccine subtypes; 3.1.4 -- Immunization sites and devices; 3.1.4.1 -- Intramuscular Immunizations; 3.1.4.2 -- Subcutaneous Immunizations; 3.1.4.3 -- Cutaneous Immunizations; 3.1.4.4 -- Mucosal Immunizations; 3.2 -- Challenges; 3.3 -- Conclusions; References; Chapter Four -- Overview of the Immune System; 4.1 -- A Short History of Immunology. 4.2 -- Immune Responses to Infection4.3 -- Innate Immunity; 4.4 -- Induced Innate Immune System; 4.4.1 -- Phagocytes; 4.4.2 -- Pattern recognition by innate immune cells; 4.4.3 -- Dendritic cells; 4.4.4 -- Natural killer cells; 4.4.5 -- Mast cells and basophils; 4.5 -- The Adaptive Immune System; 4.6 -- Cells of the Adaptive Immune System; 4.6.1 -- T cells; 4.6.2 -- B cells; 4.6.3 -- Immunological memory; 4.7 -- Immunoglobulin Classes and Function; 4.8 -- Blurring the Lines Between Innate and Adaptive Immunity; 4.8.1 -- Innate-like lymphocytes; 4.8.2 -- Innate immune cells with memory. 4.9 -- Concluding RemarksReferences; Chapter Five -- The Role of Antigen Presentation and Innate Immunity During Immune Induction by Particulate Antigens; 5.1 -- Introduction to Vaccine Adjuvants; 5.2 -- The Innate Immune System as a Regulator of Adaptive Immunity; 5.2.1 -- The relationship between innate and adaptive immune systems; 5.2.2 -- Pattern recognition receptors and their ligands; 5.3 -- Nanoparticle Vaccine Delivery Systems; 5.3.1 -- Antigens attached to inert nanoparticles; 5.3.2 -- Particulate antigens containing innate immune stimulators. 5.4 -- Targeting APCs at the Site of Vaccination and in the Draining Lymph Node.
• Publisher Details: Amsterdam : Elsevier
• Publication Date: 2017
• Copyright Date: 2017
• Extent: 1 online resource (462 pages)
• Subjects: 615.372; Vaccines -- Biotechnology; Nanomedicine; MEDICAL -- Pharmacology; Electronic books
• Languages: English
• ISBNs: 9780323400299; 0323400299
• Related ISBNs: 9780323399814; 0323399819
• Notes: Note: Includes bibliographical references and index.; Note: Online resource; title from PDF title page (EBSCO, viewed October 31, 2016).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.