Chromatin regulation and dynamics. (2016)

• Record Type: Book
• Further Information: Note: Edited by Anita Göndör.
• Other Names: Göndör, Anita
• Contents: Cover; Title page; Copyright page; Table of Contents; List of Contributors; Preface; Chapter 1 -- A Brief Introduction to Chromatin Regulation and Dynamics; 1.1 -- Introduction to Basic Concepts of Chromatin Regulation; 1.2 -- Epigenetic Phenomena: Heritability of Chromatin States During Cell Division; 1.2.1 -- Inheritance of Stable, Cell Type-Specific Gene Expression Patterns; 1.2.2 -- Genomic Imprinting; 1.2.3 -- Random Monoallelic Gene Expression; 1.2.4 -- Other Epigenetic Phenomena; 1.3 -- Reprogramming of Epigenetic States During Development and in Diseases 1.3.1 -- Reprogramming of Epigenetic Marks During Early&#x;Development1.3.2 -- Epigenetic Reprogramming in Tumor Development; 1.4 -- Early Period of Chromatin Research; 1.5 -- Discovery of the Nucleosome and Nucleosome Positioning; 1.6 -- Histone Modifications: Discovery and Function; 1.6.1 -- The Language of Histone Modifications; 1.7 -- Discovery of DNA Methylation: Functions and Cross Talk With Histone Modifications; 1.7.1 -- Discovery of DNA Methylation; 1.7.2 -- DNA Methylation in Tumor Development; 1.7.3 -- Cross Talk Between DNA Methylation and Histone Modifications 1.8 -- Replication Timing: Potential Vehicle for Epigenetic Inheritance and Reprogramming1.9 -- Chromatin Folding in 3D: Basic Principles of Genome Organization; 1.9.1 -- Cross Talk Between Regulatory Elements; 1.9.2 -- Technical Innovations to Detect 3D Genome Organization; 1.9.3 -- Compartmentalization of Nuclear Functions; 1.10 -- Signal Integration at the Level of Chromatin; 1.11 -- Outlook; Abbreviations; Acknowledgments; Conflict of Interest; References; Chapter 2 -- Histone Modifications and Histone Variants in Pluripotency and Differentiation 2.1 -- Histones and the Regulation of Transcription2.1.1 -- Histones; 2.1.1.1 -- Core and Linker Histones; 2.1.1.2 -- Histone Variants; 2.1.2 -- Histone Posttranslational Modifications; 2.1.2.1 -- Histone Acetylation; 2.1.2.2 -- Histone Methylation; 2.1.2.3 -- Context-Dependent Role of Histone Modifications; 2.1.2.4 -- Small Molecule Inhibitors of Chromatin Regulators; 2.2 -- Histone PTMs and Variants During Development; 2.2.1 -- Epigenetic Landscapes During Development; 2.2.2 -- Histone PTMs and Variants in Pluripotency and Reprogramming; 2.2.2.1 -- Unique Properties of the Chromatin of Pluripotent Cells 2.2.2.2 -- How is a Pluripotent Epigenetic State Established?2.2.2.3 -- Histone Variants in Pluripotency; 2.2.2.4 -- Histone Modifications as Barriers Against Reprogramming; 2.2.3 -- Histone PTMs/Variants in Cell Specification and Differentiation in the Developing Central Nervous System; 2.2.3.1 -- Histone (De)Methylation in Neural Development; 2.2.3.2 -- Histone (De)Acetylation in Neural Development; 2.2.4 -- Terminally Differentiated Neural Cell States: Histones in the Regulation of Functional States; 2.2.4.1 -- Histone Modifiers in Synaptic Development 2.2.4.2 -- Histone Modifiers in Neural Plasticity, Learning, and Memory
• Publisher Details: London, United Kingdom : Academic Press is an imprint of Elsevier
• Publication Date: 2016
• Extent: 1 online resource
• Subjects: 572.8/7; Chromatin; Electronic books
• Languages: English
• ISBNs: 0128034025; 9780128034026
• Related ISBNs: 9780128033951; 0128033959
• Notes: Note: Description based on print version record.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.