Aneurysms-osteoarthritis syndrome : SMAD3 gene mutations /: SMAD3 gene mutations. (2016)

• Record Type: Book
• Further Information: Note: Denise van der Linde, Jolien Roos-Hesselink, Bart L. Loeys.
• Authors: van der Linde, Denise; Roos-Hesselink, Jolien; Loeys, Bart L
• Contents: 1. Genetics (the discovery, broadened to include aspects as genotype/phenotype correlations, functional role of SMAD3, insights into the role of TGFbeta signaling in aortic disease) 2. Cardiovascular phenotype 3. Systemic features (skeletal, joints, auto-immune, craniofacial features) 4. Differential diagnosis heritable thoracic aortic diseases 5a. Marfan 5b. Loeys-Dietz 5c. Ehlers-Danlos 5d. Bicuspid aortic valve 5e. Turner Syndrome 6. Cardiovascular imaging 7. Treatment options 7a. Optimal cardiovascular medical treatment (Losartan etc.) 7b. Cardiothoracic surgical experience 7c. Vascular interventions and surgical experience 7d. Orthopedic treatment options 7e. Genetic counseling 7f. Approach to clinical management (including proposed clinical follow-up chart)
• Publisher Details: Amsterdam : Elsevier
• Publication Date: 2016
• Extent: 1 online resource
• Subjects: 616.138; Aortic aneurysms
• Languages: English
• ISBNs: 9780128027110
• Related ISBNs: 9780128027080
• Notes: Note: Description based on CIP data; item not viewed.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.