Inhibitors of molecular chaperones as therapeutic agents. (2013)

• Record Type: Book
• Further Information: Note: [edited by] Timothy D. Machajewski, Zhenhai Gao, David Rotella.
• Editors: Machajewski, Timothy D; Gao, Zhenhai
• Other Names: Rotella, David P editor compilation.
• Contents: Section I Structure and Function: Conformational Dynamics, Structure and Functional Interactions of Hsp90 Chaperones; Structural Basis of Hsp90 Function; Structure and Function of Hsp70 - TBD; Exploiting the Dependency of Cancer Cells on Molecular Chaperones; Section II Small Molecule Inhibitors; Discovery of BIIB028; Discovery of STA-9090; Discovery of Serenex Hsp90 Inhibitor; Discovery of NVP-AUY922; Discovery of NVP-HSP990; Inhibitors of Hsp90 C-Terminal Domain; Hsp70 Inhibitors; Section III Clinical Perspectives; Clinical Development of Hsp90 Inhibitors as Anti-Cancer Agents; Hsp90 as a Potential Anti-Malarial Agent; Biomarker Development and Indication Selection; Other Disease Indications
• Publisher Details: Cambridge : Royal Society of Chemistry
• Publication Date: 2013
• Extent: 1 online resource
• Subjects: 572.645; MEDICAL / Pharmacy; Molecular chaperones; Chemical inhibitors; Chemical inhibitors; Molecular chaperones; Other branches of medicine; Electronic books; Electronic books
• Languages: English
• ISBNs: 9781849739689; 1849739684; 9781849736664; 1849736669
• Notes: Note: Publisher supplied information.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.