Male-mediated developmental toxicity. (©2007)

• Record Type: Book
• Further Information: Note: Edited by Diana Anderson and Martin H. Brinkworth.
• Other Names: Brinkworth, Martin H; Anderson, Diana
• Contents: Epigenetic transgenerational actions of endocrine disruptors through the male germ-line -- Reproductive outcomes among men treated for cancer -- Paediatric cancer : an indicator of familial cancer risk? -- What harms the developing male reproductive system? -- Links between paternal smoking and childhood cancer -- Feasibility study of metal effects on the X:Y ratio in human sperm -- Use of the sperm chromatin structure assay (SCSA) as a diagnostic tool in the human infertility clinic -- Safety of sperm for use in intra-cytoplasmic sperm injection -- Male-mediated F1 effects in mice exposed to di(2-ethylhexyl)phthalate (DEHP) -- Prevention of adverse effects of cancer treatment on the germline -- Molecular changes in sperm and early embryos after paternal exposure to a chemotherapeutic agent -- Transmissible genetic risk causing tumours in mice and humans -- Heritable effects on DNA damage following paternal F0 germline irradiation -- Influence of DNA methylation and genomic imprinting in the male germ line on pregnancy outcome -- Information content of ejaculate spermatozoa and its potential utility in toxicology and infertility based research programmes -- Origin of paternal mutations -- Redox regulation of dna damage in the male germ line -- Advances in the direct measurements of partial chromosomal duplication, deletions and breaks in human and murine sperm by sperm fish -- Radiation-induced transgenerational instability in mice -- New genetic information generated by endogenous reverse transcription in sperm cells -- Sperm abnormalities in exposed humans -- Oestrogenic compounds and oxidative stress -- DNA repair capacities in testicular cells of rodents and man -- Closing panel discussion.
• Publisher Details: Cambridge, UK : Royal Society of Chemistry
• Publication Date: 2007
• Copyright Date: 2007
• Extent: 1 online resource (xxii, 292 pages), illustrations
• Subjects: 572.838; SCIENCE / Chemistry / Clinical; Mutagenesis; Antibody diversity; Spermatogenesis; Antineoplastic Agents; Environmental Exposure; Genetic Predisposition to Disease; Mutagenesis; Neoplasms; Pregnancy Outcome; SCIENCE -- Life Sciences -- Molecular Biology; Chemistry; Science; Antibody diversity; Mutagenesis; Chemistry; Developmental biology; Congresses; Electronic books
• Languages: English
• ISBNs: 9781847557643; 1847557643
• Related ISBNs: 9780854048472; 0854048472
• Notes: Note: Includes bibliographical references and index.; Note: Online resource; title from title screen (viewed on Apr. 21, 2008).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.