In silico toxicology : principles and applications /: principles and applications. (2010)

• Record Type: Book
• Further Information: Note: [edited by] Mark Cronin, Judith Madden.
• Other Names: Cronin, Mark T. D; Madden, Judith
• Contents: Introduction; Section 1: Compiling the Model; Sources of Toxicity Data for In Silico Toxicology; Calculation of Physico-Chemical Properties; Calculation of Theoretical 2-D Descriptors; Calculation of Molecular Orbital Descriptors; QSAR Methods: Receptor Modelling in Toxicology; Evaluating Data Quality; Section 2: Data Integration, Analysis and Utilisation; QSAR Methods: Statistical Methodologies; Characterisation, Evaluation and Possible Validation of a QSAR; Applicability Domain Mechanisms of Toxic Action in In Silico Toxicology; Formation of Categories; Read-Across Endpoint-Based Extrapolation; Role of Exposure in Modelling; Expert Systems Tools for Category Formation and Read-Across; Section 3: Application of In Silico Toxicology to Risk Assessment; Weight of Evidence in Toxicity Prediction; Integrated Testing Strategies; Case Study: Predicting Environmental Toxicity; Case Study: Predicting Human Health; In Silico Toxicology in Risk Assessment
• Publisher Details: Cambridge : Royal Society of Chemistry
• Publication Date: 2010
• Extent: 1 online resource (581 pages)
• Subjects: 547; SCIENCE / Chemistry / Physical & Theoretical; Organic compounds -- Toxicity testing; Animal Testing Alternatives -- methods; Toxicity Tests -- methods; Computational Biology -- methods; Organic Chemicals -- chemistry; Organic Chemicals -- toxicity; Pharmaceutical Preparations -- chemistry; SCIENCE -- Chemistry -- Organic; Quantum & theoretical chemistry; Electronic books
• Languages: English
• ISBNs: 9781849732093; 1849732094
• Related ISBNs: 9781849730044
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.