New therapeutic strategies for type 2 diabetes : small molecule approaches /: small molecule approaches. (©2012)

• Record Type: Book
• Further Information: Note: Edited by Robert M. Jones.
• Other Names: Jones, Robert M
• Contents: Type 2 diabetes: disease overview / Daniel M. Kemp -- Marketed small molecule dipeptidyl peptidase IV (DPP4) inhibitors as a new class of oral anti-diabetics / Zhonghua Pei -- SGLT2 inhibitors in development / William N. Washburn -- Glucokinase activators in development / Kevin J. Filipski, Benjamin D. Stevens and Jeffrey A. Pfefferkorn -- 11[beta]-hydroxysteroid dehydrogenase type 1 (11[beta]-HSD1) inhibitors in development / James S. Scott and Jasen Chooramun -- Recent advances in PTP1B inhibitor development for the treatment of type 2 diabetes and obesity / Rongjun He, Li-Fan Zeng, Yantao He and Zhong-Yin Zhang -- Recent advances in the discovery of GPR119 agonists / Unmesh Shah, Scott Edmondson and Jason W. Szewczyk -- Acyl-CoA: diacylglycerol acyltransferase-1 inhibition as an approach to the treatment of type 2 diabetes / Robert L. Dow -- Stearoyl-CoA desaturase 1 (SCD1) inhibitors: bench to bedside must only go through liver / Gang Liu -- TGR5 agonists in development / Antonio Macchiarulo, Antimo Gioiello and Roberto Pellicciari -- The discovery and development of MB07803, a second generation fructose-1, 6-bisphosphatase inhibitor with improved pharmacokinetic properties, as a potential treatment of type 2 diabetes / Qun Dang, Paul D. van Poelje and Mark D. Erion -- Inhibition of glycogen phosphorylase as a strategy for the treatment of type 2 diabetes / Brad R. Henke -- SIRT1 activators in development / Robert B. Perni [and others] -- Long-chain free fatty acid receptor agonists / Jonathan B. Houze -- Glucagon receptor antagonists in development / Duane E. DeMong and M.W. Miller -- ACC inhibitors in development / Matthew P. Bourbeau.
• Publisher Details: Cambridge : Royal Society of Chemistry
• Publication Date: 2012
• Copyright Date: 2012
• Extent: 1 online resource (xv, 515 pages), illustrations
• Subjects: 572/.58; Chemistry; Diabetes -- Treatment; Diabetes Mellitus, Type 2 -- drug therapy; Drug Discovery; SCIENCE -- Life Sciences -- Biochemistry; Diabetes -- Treatment; Pharmacology; Electronic books
• Languages: English
• ISBNs: 9781849735322; 1849735328
• Related ISBNs: 9781849734141; 1849734143
• Notes: Note: Includes bibliographical references and index.; Note: Print version record.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.