Advances in polyurethane biomaterials. (2016)

• Record Type: Book
• Further Information: Note: Edited by Stuart L. Cooper, Jianjun Guan.
• Editors: Cooper, Stuart L, 1941-; Guan, Jianjun
• Contents: Front Cover; Related titles; Advances in Polyurethane Biomaterials; Copyright; Contents; List of contributors; Woodhead Publishing Series in Biomaterials; Preface; One -- Chemistry, processing and applications of polyurethane biomaterials; 1 -- Hierarchal structure-property relationships of segmented polyurethanes; 1.1 Introduction; 1.2 Structure of segmented polyurethanes; 1.2.1 Polyurethane reactions; 1.2.2 Segmented polyurethane elastomers; 1.3 Soft segment chemistry; 1.3.1 Polyester soft segments; 1.3.2 Polyether soft segments; 1.3.3 Triblock soft segments; 1.4 Hard segment chemistry. 1.4.1 Isocyanates1.4.2 Chain extenders; 1.5 Microphase separation; 1.5.1 Thermodynamics; 1.5.2 Structural morphology; 1.5.3 Kinetics; 1.6 Compositional effects on mechanical properties; 1.6.1 Effect of the soft segment; 1.6.2 Effect of hard segment; 1.7 Compositional effects on degradation rate; 1.7.1 Effect of soft segment; 1.7.2 Effect of hard segment; 1.8 Summary and future perspectives; References; 2 -- Surface characterization techniques for polyurethane biomaterials; 2.1 Friction measurement; 2.1.1 Coefficient of friction measurement; 2.1.2 Trackability measurement; 2.2 Contact angle. 2.2.1 Static sessile drop2.2.2 Dynamic contact angle; 2.2.2.1 Dynamic sessile drop; 2.2.2.2 Wilhelmy plate; 2.3 X-ray photoelectron spectroscopy; 2.4 Secondary ion mass spectrometry; 2.5 Scanning electron microscopy; 2.6 Protein adsorption test; 2.6.1 Quartz crystal microbalance; 2.6.2 Iodination radiolabeling; 2.7 Hemocompatability measurement; 2.7.1 In vitro platelet adhesion; 2.7.1.1 Radioactive isotope labeling; 2.7.1.2 Lactate dehydrogenase assay; 2.7.1.3 Acid phosphatase assay; 2.7.2 Scanning electron microscopy; 2.7.3 In vitro blood loop method; 2.7.4 Ex vivo shunt blood loop. 2.8 Antimicrobial efficacy test2.8.1 Zone of inhibition; 2.8.2 Contact kill; 2.9 Antibiofilm efficacy; 2.9.1 Minimum biofilm eradication concentration assay; 2.9.2 Scanning electron microscopy; 2.9.3 Flow cell assay; Acknowledgments; References; 3 -- Design of biodegradable polyurethanes and the interactions of the polymers and their degradation by-products within in vitro and in vivo environments; 3.1 Fundamentals of polyurethane degradation; 3.1.1 Polyurethane chemistry influences stability; 3.1.2 Polyurethane bulk degradation; 3.1.3 Hydrolytic degradation. 3.1.4 Molecular mechanisms at the cell-material interface3.1.5 Environmental biodegradation; 3.2 Design of new degradable polyurethanes inspired by biodegradation mechanisms; 3.2.1 Degradable polyurethanes designed with hydrolytically susceptible soft segments; 3.2.2 Degradable polyurethanes developed with blended soft segments; 3.2.3 Degradable polyurethanes with varying chain extenders; 3.2.4 Degradable polyurethanes generated from novel chemistries; 3.3 In vivo testing of polyurethanes from 2005 to 2015.
• Publisher Details: Duxford : Woodhead Publishing
• Publication Date: 2016
• Extent: 1 online resource
• Subjects: 668.4239; Polyurethanes; Biomedical materials; TECHNOLOGY & ENGINEERING / Chemical & Biochemical; Biomedical materials; Polyurethanes; Electronic books
• Languages: English
• ISBNs: 9780081006221; 0081006225
• Related ISBNs: 9780081006146
• Notes: Note: Vendor-supplied metadata.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.