Understanding and exploiting protein-protein interactions as drug targets. ([2013])

• Record Type: Book
• Further Information: Note: Editor, Giovanna Zinzalla.
• Editors: Zinzalla, Giovanna
• Other Names: Future Science Ltd., publisher.
• Contents: Understanding and exploiting protein-protein interactions as drug targets / Giovanna Zinzalla -- Protein-protein interactions : an emerging class of molecular targets for anticancer drugs / Alex W. White, Jitka Soukupová & Andrew D. Westwell -- Druggability of protein-protein interactions / Veronique Hamon & Xavier Morelli -- Chemical library screening approaches to aid the design of protein-protein inhibitors / Luca Laraia & David R. Spring -- Peptides as protein-protein interaction modulators / Erika Nieddu, Luisa Merello & Carlo Bidoia -- Constrained peptide helices / Andrew B. Mahon & Paramjit S. Arora -- Synthesis of peptidomimetic scaffolds / Andrew J. Wilson -- Computational approaches for the design of protein-protein interaction inhibitors / Wenbo Yu, Olgun Guvench & Alexander D. MacKerell Jr. -- Biochemical assays and biophysical tools for inhibitor identification and validation / Adrian Fowkes, Helene Bertrand & Geoff Wells -- Cell-based assays for identifying, validating and optimizing protein-protein interaction modulators / Abigail L. Male & Ali Tavassoli -- Future directions / Alexander L. Breeze -- Index.
• Publisher Details: London, England : Future Science Ltd (Unitec House, 2 Albert Place, London N3 1QB, UK)
• Publication Date: 2013
• Extent: 1 PDF (152 pages), color illustrations, digital file
• Subjects: 615/.19; Protein-protein interactions; Drug development; Drug development; Protein-protein interactions; Proteins -- metabolism; Drug Discovery -- methods; Electronic books
• Languages: English
• ISBNs: 9781909453463; 1909453463; 9781909453456; 1909453455
• Related ISBNs: 9781909453470
• Notes: Note: Includes bibliographical references and index.; Note: Title from PDF title page (Future Science eBooks Web site, viewed November 18, 2013).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.