Epi-informatics : discovery and development of small molecule epigenetic drugs and probes /: discovery and development of small molecule epigenetic drugs and probes. ([2016])

• Record Type: Book
• Further Information: Note: Editor: José L. Medina-Franco, PhD, Faculty of Chemistry, Departmant of Pharmacy, National Autonomous University of Mexico, Mexico City, Mexico.
• Editors: Medina-Franco, José L
• Contents: Introduction of Epigenetic Targets in Drug Discovery and Current Status of Epi-Drugs and Epi-Probes Overview of Computer-Aided Drug Design for Epigenetic Targets Structure-Guided Optimization of DNA Methyltransferase Inhibitors Discovery and Development of Small Molecules Targeting Epigenetic Enzymes with Computational Methods Insilico Optimization of the First DNA-Independent Mechanism-Based Inhibitor of Mammalian DNA Methyltransferase DNMT1 Structure-Based Modeling of Histone Deacetylases Inhibitors Searching Histone Deacetylase Inhibitors under Computational Procedures Current Development of Protein Arginine Methyltransferase Inhibitor Molecular Design of Compounds Targeting Histone Methyltransferases Computational Chemical Biology of Methyllysine Histone Effectors Structure-Based Design and Computational Studies of Sirtuin Inhibitors Drug Repurposing for Epigenetic Targets Guided by Computational Methods Computational Structure–Activity Relationship Studies of Epigenetic Target Inhibitors Role of Nutrition in Epigenetics and Recent Advances of In Silico Studies The Road Ahead of the Epi-Informatics Field .
• Publisher Details: London : Academic Press
• Publication Date: 2016
• Extent: 1 online resource, illustrations (black and white, and colour)
• Subjects: 615.19; Drug development; Drug development -- Computer simulation; Epigenetics
• Languages: English
• ISBNs: 9780128028094; 0128028092
• Related ISBNs: 9780128028087
• Notes: Note: Includes bibliographical references and index.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.