New trends in basic and clinical research of glaucoma. a neurodegenerative disease of the visual system /: a neurodegenerative disease of the visual system. Part A : (2015)

• Record Type: Book
• Further Information: Note: Volume editors, Giacinto Bagetta, Carlo Nucci.
• Editors: Bagetta, Giacinto; Nucci, Carlo
• Contents: ""Title page""; ""Table of Contents""; ""Copyright""; ""Contributors""; ""Preface""; ""Part A""; ""Chapter 1: Retinal neurodegeneration in experimental glaucoma""; ""Abstract""; ""1 Introduction""; ""2 Methods""; ""3 Results and Discussion""; ""4 Concluding Remarks""; ""Acknowledgments""; ""Chapter 2: Retinal ganglion cell apoptotic pathway in glaucoma: Initiating and downstream mechanisms""; ""Abstract""; ""1 Introduction""; ""2 The Initial Insult-BDNF and Neurotrophic Factor Deprivation""; ""3 The MAP-Kinase Pathway in Glaucoma""; ""4 JNK""; ""5 p38""; ""6 ERK""; ""7 The BCL-2 Family"" ""8 Caspases and Inhibitor of Apoptosis Proteins""""9 Normal Tension Glaucoma""; ""10 Limitations""; ""11 Summary""; ""Chapter 3: The contribution of the sclera and lamina cribrosa to the pathogenesis of glaucoma: Diagnostic and treatment implications""; ""Abstract""; ""1 Introduction""; ""2 The Interaction of PPS, Lamina Cribrosa, and IOP""; ""3 Pathological Changes in the Sclera and ONH in Glaucoma""; ""4 Role of Experimental Animal Models""; ""5 Scleral and ONH Changes in Mouse Glaucoma""; ""6 Remodeling of the ONH in Glaucoma"" ""7 Connective Tissue-Based Therapies to Alter Glaucoma Damage""""8 Conclusion""; ""Acknowledgments""; ""Chapter 4: Autophagy dysregulation and the fate of retinal ganglion cells in glaucomatous optic neuropathy""; ""Abstract""; ""1 Introduction""; ""2 The Basics of Autophagy: Mechanisms, Regulation, and Functions""; ""3 Autophagy and RGC Death in Glaucoma Models""; ""4 Aging, Autophagy, and Glaucoma""; ""5 Concluding Remarks""; ""Acknowledgment""; ""Chapter 5: Advances in glaucoma genetics""; ""Abstract""; ""1 Introduction""; ""2 Familial Linkage Analysis: causative POAG Disease Genes"" ""3 Association Studies for POAG""""4 Perspective""; ""Chapter 6: Oxidative stress and mitochondrial failure in the pathogenesis of glaucoma neurodegeneration""; ""Abstract""; ""1 Introduction""; ""2 Mitochondrial Involvement in Glaucoma Pathogenesis""; ""3 Oxidative Stress in Eye Diseases""; ""4 Antioxidants and Glaucoma. Improving Glaucoma Prognosis by Applying Targeted Neuroprotection""; ""5 Final Remarks""; ""Chapter 7: Macro- and microglial responses in the fellow eyes contralateral to glaucomatous eyes""; ""Abstract""; ""1 Introduction"" ""2 The Contralateral Eye is Involved in Some Experimental Glaucoma Models""""3 RGC Damage After Axonal Injury: Optic-Nerve Crush and Optic-Nerve Section""; ""4 RGC Damage After IOP Elevation""; ""5 Mechanisms Responsible for Contralateral Eye Involvement""; ""Acknowledgments""; ""Chapter 8: Retinal and optic nerve changes in glaucoma: From animal study to clinical implication""; ""Abstract""; ""1 Introduction""; ""2 Confocal Scanning Laser Tomography""; ""3 Scanning Laser Polarimetry""; ""4 Spectral Domain Optical Coherence Tomography""
• Publisher Details: Amsterdam : Elsevier
• Publication Date: 2015
• Extent: 1 online resource
• Subjects: 617.741; Glaucoma; MEDICAL -- Surgery -- General; Glaucoma; Electronic books
• Languages: English
• ISBNs: 9780444635693; 0444635696
• Related ISBNs: 9780444635662; 9780128046081; 0128046082; 0444635661
• Notes: Note: CIP data; item not viewed.
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