Novel anticancer agents : strategies for discovery and clinical testing /: strategies for discovery and clinical testing. (2011)

• Record Type: Book
• Further Information: Note: Editors, Alex A. Adjei, John K. Buolamwini.
• Other Names: Adjei, Alex A; Buolamwini, John K
• Contents: A survey of novel molecular targets for anticancer drug discovery -- Microarrays: small spots produce major advances in pharmacogenomics -- Strategies to target chemotherapeutics to tumors -- QSAR and pharmacophore mapping strategies in novel anticancer drug discovery -- Applications of nuclear magnetic resonance and mass spectrometry to anticancer drug discovery -- Antisense strategies for the development of novel cancer therapeutics -- Antibodies and vaccines as novel cancer therapeutics -- Inhibitors as targets for cancer therapy -- Preclinical testing and validation of novel anticancer agents -- Surrogate end points and biomarkers for early trials of novel anticancer agents -- Regulatory considerations in clinical trials of novel anticancer drugs -- Improving the efficacy and safety of anticancer agents: the role of pharmacogenetics -- Imaging of pharmacodynamic end points in clinical trials -- Devising proof-of-concept strategies in oncology clinical trials -- Clinical trial designs for cytostatic agents and agents directed at novel molecular targets -- Cancer gene therapy clinical trials: from the bench to the clinic -- Molecular targets for radiosensitization -- Patient accrual to clinical trials.
• Publisher Details: Place of publication not identified : Academic Press
• Publication Date: 2011
• Extent: 1 online resource (464 pages)
• Subjects: 616.994061; Antineoplastic agents -- Development; Antineoplastic agents -- Testing; Antineoplastic Agents; Drug Therapy; Research -- methods; Drug Screening Assays, Antitumor; Clinical Trials -- methods; Pharmacogenetics
• Languages: English
• ISBNs: 9780080537757; 0080537758
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.