Principles of behavioral genetics. (2009)

• Record Type: Book
• Further Information: Note: Robert R.H. Anholt, Trudy F.C. Mackay.
• Other Names: Anholt, Robert Rene Henri, 1951-; Mackay, Trudy F. C
• Contents: Preface; ; Chapter 1: Introduction and Historical Perspective; ; Overview; ; The Rise of the Modern Field of Behavioral Genetics; ; The Modern Evolutionary Synthesis; ; The Rise of Molecular Genetics; ; A Brief History of Neuroscience; ; The Emergence of Behavioral Genetics; ; Summary; ; Study Questions; ; Recommended Reading; ; Chapter 2: Mechanisms of Neural Communication; ; Overview; ; Transmission of Information in the Nervous System; ; The Resting Membrane Potential; ; The Mechanism of the Action Potential; ; Ion Channels, G-protein-coupled Receptors, and Signal Transduction; ; Summary; ; Study Questions; ; Recommended Reading; ; Chapter 3: Functional Organization of the Nervous System; ; Overview; ; The Organization of the Mammalian Nervous System; ; Communication between the Brain and the Periphery; ; Organization of the Nervous System in Insects; ; Neurotransmitters; ; Summary; ; Study Questions; ; Recommended Reading; ; Chapter 4: Measuring Behavior: Sources of Genetic and Environmental Variation; ; Overview; ; Behavioral Assays; ; Controlling Experimental Variation; ; Sources of Variation in Behavior; ; Effects of Mutations on Behavioral Phenotypes; ; Environmental Variation; ; Gene - Environment Correlation and Interaction; ; Summary; ; Study Questions; ; Recommended Reading; ; Chapter 5: Mapping Genotype to Phenotype in Populations; ; Overview; ; Genes in Populations: Random Mating; ; Genes in Populations: Inbreeding; ; Quantitative Genetic Model; ; Summary; ; Study Questions; ; Recommended Reading; ; Chapter 6: Partitioning Phenotypic Variance and Heritability; ; Overview; ; Components of Variance in Random Mating Populations; ; Genotype-Environment Correlation and Interaction; ; Partitioning Phenotypic Variance; ; Heritability : The Concept; ; Controlling and Estimating Environmental Components of Variation; ; Summary; ; Study Questions; ; Recommended Reading; ; Chapter 7: Estimating Heritability; ; Overview; ; Phenotypic Resemblance between Relatives; ; Genetic Causes of Covariance between Relatives; ; Environmental Causes of the Relationship between Relatives; ; Heritability Estimates in Humans; ; Heritability in Other Populations; ; Estimates of Heritability for Behavioral Traits; ; Summary; ; Study Questions; ; Recommended Reading; ; Chapter 8: Quantitative Trait Locus Mapping; ; Overview; ; Linkage Mapping; ; Interval Mapping; ; Statistical Analysis; ; Association Mapping; ; Quantitative Trait Locus End Game; ; Summary; ; Study Questions; ; Recommended Reading; ; Chapter 9: Mutagenesis and Transgenesis; ; Overview; ; The Occurrence or Induction of Mutations; ; Homologous Recombination; ; Transposon -mediated Mutagenesis; ; The GAL4-UAS Binary Expression System in Drosophila; ; RNA Interference; ; Summary; ; Study Questions; ; Recommended Reading; ; Chapter 10: Genomics Approaches in Behavioral Genetics; ; Overview; ; Detecting Large-scale Gene Expression; ; Parallel Sequencing and Transcriptional Analysis; ; Plasticity of Transcriptional Profiles; ; Analysis of Whole-genome Expression Microarray; ; Defining Statistical Signifi cance Threshold; ; Identifying Genetic Networks; ; Summary; ; Study Questions; ; Recommended Reading; ; Chapter 11: Neurogenetics of Activity and Sleep; ; Overview; ; Locomotion; ; Genetics of Human Locomotion Disorders; ; Circadian Rhythms; ; Sleep; ; Summary; ; Study Questions; ; Recommended Reading; ; Chapter 12: Genetics of Social Interactions; ; Overview; ; Social Environment and the Genes-Brain-Behavior Paradigm; ; Social Cooperation and Fitness; ; Courtship and Mate Selection; ; Affiliative Behavior; ; Aggression and the Establishment of Social Hierarchies; ; Division of Labor: The Genetics of Social Structure; ; Aggregation Behavior; ; Summary; ; Study Questions; ; Recommended Reading; ; Chapter 13: Genetics of Olfaction and Taste; ; Overview; ; The Study of Olfaction; ; The Discovery of Odorant Receptors; ; Transgenic Approaches to Determine Odorant Receptor Response Profiles; ; Transgenic Approaches to Map Projection Patterns of Olfactory Sensory Neurons; ; The Use of Transgenic Reporter Genes to Visualize Odor Coding; ; Taste and Gustatory Receptors; ; Summary; ; Study Questions; ; Recommended Reading; ; Chapter 14: Learning and Memory; ; Overview; ; Forming Memories; ; Memory Formation: Cellular Mechanisms; ; Harnessing the Power of Genetics: Learning in Drosophila; ; Identifying Genetic Networks for Learning and Memory; ; Learning Disabilities; ; Neurodegeneration and Memory Impairment: Alzheimer’s Disease; ; Summary; ; Study Questions; ; Recommended Reading; ; Chapter 15: Genetics of Addiction; ; Overview; ; Hallmarks of Addiction; ; Alcoholism; ; Linkage and Association Studies; ; Alcohol Sensitivity in Model Organisms; ; Alcohol-related Phenotypes in Rodent Models; ; Smoking; ; Drug Addiction; ; Summary; ; Study Questions; ; Recommended Reading; ; Chapter 16: Evolution of Behavior; ; Overview; ; Population Genetics and Evolution; ; Models of Evolution; ; Selection Models; ; Assessing Deviations from Neutrality; ; Behavior as a Vehicle for Evolution; ; Insect-Host Plant Interactions: An Example of Evolutionary Adaptation; ; Co-evolution of Sexual Communication Systems; ; Study Questions; ; Recommended Reading; ; Chapter 16: Evolution of Behavior; ; Overview; ; Population Genetics and Evolution; ; Models of Evolution; ; Selection Models; ; Assessing Deviations from Neutrality; ; Behavior as a Vehicle for Evolution; ; Insect-Host Plant Interactions: An Example of Evolutionary Adaptation; ; Co-evolution of Sexual Communication Systems; ; The Evolutionary Genetics of Burrowing and Nest Building; ; The Astounding Diversity of Cichlids and Sticklebacks; ; Understanding the Evolution of Behavior: How Much Do We Really Know?; ; Summary; ; Study Questions; ; Recommended Reading; ; Glossary; ; Index; ; ;
• Publisher Details: Place of publication not identified : Academic Press
• Publication Date: 2009
• Extent: 1 online resource (334 pages)
• Subjects: 155.7; Behavior genetics
• Languages: English
• ISBNs: 9780080919898; 0080919898
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.