Vitamin D. ([2005])

• Record Type: Book
• Further Information: Note: David Feldman, J. Wesley Pike, Francis H. Glorieux.
• Authors: Feldman, David, 1939-; Glorieux, Francis H; Pike, J. Wesley
• Editors: Feldman, Daṿid; Pike, J. Wesley; Glorieux, Francis H
• Contents: INTRODUCTION; CH 1: Historical Perspective; ; SECTION I: CHEMISTRY, METABOLISM, AND CIRCULATION; CH 2: Vitamin D Metabolism; CH 3: Photobiology of Vitamin D; CH 4: The Vitamin D-25 Hydroxylase; CH 5: The 25-Hydroxyvitamin D 1-alpha-Hydroxylase; CH 6: The 25-Hydroxyvitamin D 24-Hydroxylase; CH 7: Mutant Mouse Models of Vitamin D Metabolic Enzymes; CH 8: Vitamin D Binding Protein; CH 9: New Aspects of DBP; CH 10: Endocytic Pathways for 25-(OH) Vitamin D3; ; SECTION II: MECHANISM OF ACTION; CH 11: The Vitamin D Receptor; CH 12: Vitamin D Receptor Promoter and Regulation of Receptor Expression; CH 13: Nuclear Vitamin D Receptor: Structure-Function, Molecular Control of Gene Transcription, and Novel Bioactions; CH 14: Vitamin D Receptor Cofactors: Function, Regulation, and Selectivity; CH 15: VDR LBD Crystal Structures; CH 16: Comodulators of VDR-Mediated: Gene Expression; CH 17: Promoter Targeting of VDR Through A Chromatin Remodeling Complex; CH 18: Molecular Basis of the Diversity of Vitamin D Target Genes; CH 19: Intranuclear Organization of the Regulatory Machinery for Vitamin D-Mediated Control of Skeletal Gene; CH 20: Mouse Models of Vitamin D Receptor Ablation; CH 21: Intranuclear Vitamin D Response Element Binding; CH 22: VDR and RXR Subcellular Trafficking; CH 23: 1a, 25(OH)2¡Vvitamin D3 mediated rapid and genomic responses are dependent upon critical structure-function relationships for both the ligand and receptor(s); ; SECTION III: MINERAL HOMEOSTASIS; CH 24: Vitamin D and the Intestinal Absorption of Calcium: A View and Overview; CH 25: Intestinal Calcium Absorption: Lessons from Knock Out Mice and Men; CH 26: Phosphate Homeostasis; CH 27: Mineralization; CH 28: Modeling and Remodeling: How Bone Cells Work Together; CH 29: Vitamin D and the Kidney; CH 30: Vitamin D and the Parathyroids; CH 31: Calcium-Sensing Receptor; ; SECTION IV: TARGET ORGANS AND ACTIONS; A. Organs/Tissues; CH 32: Bone; CH 33: Cartilage and Vitamin D: Genomic and Nongenomic Regulation; CH 34: Dento-Alveolar Bone Complex and Vitamin D; CH 35: Role in Skin and Hair; CH 36: Regulation of Immune Responses by Vitamin D Receptor Ligands; CH 37: Osteoblasts; CH 38: Vitamin D and Osteoclastogenesis; CH 39: Vitamin D Control of the Calcitonin Gene in Thyroid C Cells; CH 40: Vitamin D Regulation of Type I Collagen Expression in Bone; CH 41: Target Genes: Bone Proteins; CH 42: The Calbindins: Calbindin-D9k and Calbindin-D28k; CH 43: Target Genes; CH 44: Effects of 1, 25-Dihydroxyvitamin D3 on Voltage-Sensitive Calcium Channels in the Vitamin D Endocrine System; CH 45: Vitamin D and the Cellular Response to Oxidative Stress; ; SECTION V: HUMAN PHYSIOLOGY; CH 46: Vitamin D: Role in the Calcium Economy; CH 47: Effects of Race, Geography, Body Habitus, Diet, and Exercise on Vitamin D Metabolism; CH 48: Perinatal Vitamin D Actions; CH 49: Vitamin D Deficiency and Calcium Absorption During Infancy and Childhood; CH 50: Vitamin D Metabolism and Aging; CH 51: Vitamin D Metabolism in Pregnancy and Lactation; CH 52: Vitamin D and Reproductive Organs; CH 53: Vitamin D Receptor as a Sensor for Toxic Bile Acids; CH 54: The Renin-Angiotensin System; CH 55: Vitamin D and Muscle; CH 56: Vitamin D and Cardiovascular Medicine; ; SECTION VI: DIAGNOSIS AND MANAGEMENT; CH 57: Approach to the Patient with Metabolic Bone Disease; CH 58: Detection of Vitamin D and Its Major Metabolites; CH 59: Bone Histomorphometry; CH 60: Radiology of Rickets and Osteomalacia; CH 61: The Pharmacology of Vitamin D, Including Fortification Strategies; ; SECTION VII: DISORDERS OF THE VITAMIN D: ENDOCRINE SYSTEM; CH 62: How to Define Normal Values for Serum Concentrations of 25-Hydroxyvitamin D? An Overview; CH 63: Vitamin D and the Pathogenesis of Rickets and Osteomalacia; CH 64: The Hypocalcemic Disorders: Differential Diagnosis and Therapeutic Use of Vitamin D; CH 65: Vitamin D Deficiency and Nutritional Rickets in Children; CH 66: Vitamin D Insufficiency in Adults and the Elderly; CH 67: Vitamin D and Osteoporosis; CH 68: Genetic Vitamin D Receptor Polymorphisms and Risk of; CH 69: Clinical Disorders of Phosphate Homeostasis; CH 70: Disorders of Phosphate Metabolism: Autosomal Dominant Hypophosphatemic Rickets, Tumor Induced Osteomalacia, Fibrous Dysplasia, and the Pathophysiological Relevance of FGF23 TIO, ADDR FGF-23; CH 71: Vitamin D Pseudodeficiency; CH 72: Hereditary 1, 25-Dihydroxyvitamin D Resistant Rickets; CH 73: Glucocorticoids and Vitamin D; CH 74: Drug and Hormone Effects on Vitamin D Metabolism; CH 75: Bone Disorders Associated with Gastrointestinal & Hepatobiliary Disease; CH 76: Vitamin D and Renal Failure; CH 77: Idiopathic Hypercalciuria and Nephrolithiasis; CH 78: Hypercalcemia Due to Vitamin D Toxicity; CH 79: Extra-renal 1„´-hydroxylase Activity and Human Disease; ; SECTION VIII: NEW VITAMIN D ANALOGS; CH 80: Overview: Rational Design of 1a, 25-Dihydroxyvitamin D3 Analogs (Deltanoids); CH 81: Analog Metabolism; CH 82: Mechanisms for the Selective Actions of Vitamin D Analogs; CH 83: Molecular Basis for Differential Action of Vitamin D Analogs; CH 84: Development of New Vitamin D Analogs; CH 85: Geminis: The 1, 25-dihydroxy Vitamin D Analogs with Two Side-Chains; CH 86: Development of OCT and ED-71; CH 87: 2-Carbon-Modified Analogs of 19-Nor- 1a, 25-Dihydroxyvitamin D3; CH 88: Non-steroidal Analogs; ; SECTION IX: VITAMIN D AND CANCER; CH 89: Vitamin D: Cancer and Differentiation; CH 90: Vitamin D, Sunlight, and the Natural History of Prostate Cancer; CH 91: Epidemiology of Cancer Risk: Vitamin D and Calcium; CH 92: Differentiation and the Cell Cycle; CH 93: Vitamin D and Breast Cancer; CH 94: Vitamin D and Prostate Cancer; CH 95: Vitamin D and Colon Cancer; CH 96: Vitamin D and Hematological: Malignancy; CH 97: Clinical Development of Calcitriol and Calcitriol Analogs in Oncology: Progress and Considerations for Future Development; ; SECTION X: EMERGING USES; Overview: Vitamin D Vs. Calcium Effects; CH 98: Vitamin D3: Autoimmunity and Immunosuppression; CH 99: Vitamin D and Diabetes; CH 100: Vitamin D, A Neuroactive Hormone: From Brain Development to Neurodegenerative Disorders; CH 101: Psoriasis and Other Skin Diseases; CH 102: Muscles and Falls; CH 103: Renal Failure and Secondary Hyperparathyroidism; CH 104: Inhibition of Benign Prostatic Hyperplasia by Vitamin D Receptor Ligands
• Edition: Second edition
• Publisher Details: London : Academic Press
• Publication Date: 2005
• Copyright Date: 2005
• Extent: 1 online resource, illustrations (black and white)
• Subjects: 615.328; Vitamin D
• Languages: English
• ISBNs: 9780080543642; 0080543642
• Notes: Note: Includes bibliographical references and index.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.