Surgical research. (2001)

• Record Type: Book
• Further Information: Note: Edited by Wiley W. Souba, Douglas W. Wilmore.
• Other Names: Souba, Wiley W; Wilmore, Douglas W (Douglas Wayne), 1938-
• Contents: Getting started -- Assessing available information -- Organizing and preliminary planning for surgical research -- Writing a protocol: animals, humans, and use of biologic, chemical, and radiologic agents -- Grantsmanship -- Informed consent and the protection of human research subjects: historical perspectives and guide to current United States regulations -- Animal care and maintenance -- Funding strategies and agencies: academic-industrial relationships; intellectual property -- Statistical considerations -- Use of nonexperimental studies to evaluate surgical procedures and other interventions: the challenge of risk adjustment -- Measuring surgical outcomes -- Design of clinical trials -- Using administrative data for clinical research -- Research in the intensive care unit: ethical and methodological issues -- Research in the operating room -- Effects of age and gender -- Strategies, principles, and techniques using transgenic and knockout mouse models -- Tissue culture, cell growth, and analysis -- Hematopoietic stem cells: basic concepts and applications to surgical research -- Basic molecular biological methods in surgical research: genetic library construction, screening, and DNA sequencing -- Transcription -- Signal transduction and apoptosis -- Mechanisms and regulation of eukaryotic protein synthesis -- Organelle studies: mitochondria, golgi, and endoplasmic reticulum -- Membrane biology and biophysics -- Molecular epidemiology: beyond gene discovery to clinical diagnostic tools. Shock models: hemorrhage -- Scoring systems for trauma research -- Blunt trauma models: fractures, chest trauma, head injury, soft-tissue trauma, and abdominal trauma -- Trauma models for studying the influence of gender and aging -- Animal models of burn injury -- Wound care models -- Models of adult respiratory distress syndrome -- aspiration -- Tumor angiogenesis -- Approaches to adoptive immunotherapy -- Metastasis: biology and experimental models -- Cancer genetics -- Cancer gene therapy -- Active immunotherapy for cancer -- Gastrointestinal motility -- Models of intestinal secrection and absorption -- Surgical models of inflammatory bowel disease -- Intestinal regeneration and adaptation models -- Minimally invasive surgery -- Experimental models and endpoints for studies of intestinal ischemia-reperfusion injury -- Gut barrier failure -- Developmental studies in the gastrointestinal tract. Animal models of liver failure -- Portal hypertension and portacaval shunt -- Animal models of liver regeneration -- Animal models for the study of hepatocyte transplantation -- Biliary stone formation -- Models for the study of pancreatitis -- Models of endocrine insufficiency -- Animal models in transplantation -- Models to study surgical nutrition and metabolism -- Stable isotopes -- Body composition -- Energetics -- Models of protein metabolism --Membrane transport of nutrients -- Models of wound healing in growth factor studies -- Animal models of sepsis and the multiple organ dysfunction syndrome -- The immuno-inflammatory response -- Antibiotic trials -- Scoring systems for sepsis and the multiple organ dysfunction syndrome -- Cytokine biology -- Biology of nitric oxide: measurement, modulation, and models -- Endothelial cell and smooth muscle cell biology in vascular disease -- Coagulation biology -- Endovascular research: stents -- Noninvasive vascular measurements -- Techniques to study microcirculation -- Blood substitutes in surgery -- Research models in pediatric surgery -- Research in fetal surgery -- Research in plastic surgery -- Research methods in neurosurgery --Research in urologic surgery -- Research in cardiac surgery -- Research in orthopedic surgery -- Statistical analysis -- specific statistical tests: indications for use. Data presentation: how to write and submit abstracts and papers -- Audiovisual communications as a research skill -- rganizing and managing meetings and conferences -- The management and organization of a surgical research laboratory -- History and philosophy of surgical research -- The surgical research program as a business enterprise -- Nobel laureates in surgery -- Surgical education research -- Mathematical modeling -- Information resource discovery for surgeons: databases and the Internet -- How to review a manuscript -- Academic surgical mentoring -- Ethics and surgical research -- The National Institutes of Health: procedures and performance -- Measuring the performance of surgical research -- Virtual reality and surgery -- Surgeons and health services research -- From idea to product: financing and regulatory issues in product development.
• Publisher Details: Place of publication not identified : Academic Press
• Publication Date: 2001
• Extent: 1 online resource (1460 pages)
• Subjects: 617.0072; Surgery -- Research; Surgical Procedures, Operative; Research Design; Projet recherche; Procédés chirurgicaux; Surgery -- Research; Chirurgie -- Recherche; Cirugía -- Investigación
• Languages: English
• ISBNs: 9780080542140
• Related ISBNs: 008054214X
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.