Phosphodiesterase inhibitors. (1996)

• Record Type: Book
• Further Information: Note: Edited by Christian Schudt, Gordon Dent and Klaus F. Rabe.
• Other Names: Schudt, Christian; Dent, Gordon; Rabe, Klaus F
• Contents: Identification and quantification of PDE isoenzymes and subtypes by molecular biological methods -- Analysis of PDE isoenzyme profiles in cells and tissues by pharmacological methods -- Effects of theophylline and non-selective xanthine derivatives on PDE isoenzymes nad cellular function -- Ca2+/calmodulin-dependent cyclic nucleotide phosphodiesterase (PDEI) -- EHNA as an inhibitor of PDE2; a pharmacological and biochemical study in cardiac myocytes -- cGMP-inhibited phosphodiesterases (PDE3) -- Interaction of PDE4 inhibitors with enzymes and cell functions -- Inhibition of phosphodiesterase isoenzymes and cell function by selective PDE5 inhibitors -- Design and synthesis of xanthines and cyclic GMP analogues as potent inhibitors of PDE5 -- Enzymatic and functional aspects of dual-selective PDE3/4 inhibitors -- An isoform-selective inhibitor of cyclic AMP-specific phosphodiesterase (PDE4) with anti-inflammatory properties -- Characterization of different states of PDE4 by rolipram and RP 73041 -- Molecular aspects of inhibitor interaction with PDE4.
• Publisher Details: Place of publication not identified : Academic Press
• Publication Date: 1996
• Extent: 1 online resource (228 pages)
• Subjects: 612.01513 P565; 615.704; Phosphodiesterases -- Inhibitors; Phosphodiesterases -- Inhibitors -- Therapeutic use; Immunpharmakologie; Inhibitor; Phosphodiesterasen; Aufsatzsammlung; Phosphodiesterase Inhibitors -- pharmacology; Phosphodiesterase Inhibitors -- therapeutic use; Aufsatzsammlung
• Languages: English
• ISBNs: 9780080538815; 0080538819
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.