ABC proteins : from bacteria to man /: from bacteria to man. (©2003)

• Record Type: Book
• Further Information: Note: Editors Ian Barry Holland [and three others].
• Other Names: Holland, I. B
• Contents: Preface. -- Introduction. -- PART 1-PHYLOGENY AND EVOLUTION OF ABC-TRANSPORTERS -- Phylogenetic and Functional Classification of ABC (ATP-binding cassette) Systems -- Membrane Topology of the Human ABC Transporter Proteins -- Human and Drosophila ABC-Proteins -- PART 2-FUNDAMENTAL ASPECTS OF THE MECHANISM OF ACTION OF ABC-TRANSPORTERS -- Structure and Modular Organization of ABC-Transporters -- Substrate Binding Sites in ABC-Transporters -- Probing of Conformational Changes, Catalytic Cycle and ABC-Transporters Function -- X-ray Structure of an Intact ABC-Transporter, MsbA -- PART 3-PROKARYOTE ABC-TRANSPORTERS -- Introduction to Bacterial ABC-Transport Systems -- Import of Solutes by ABC-Transporters-The Maltose System -- Crystal Structures of Periplasmic Solute Binding Proteins in ABC-Transport Complexes Illuminate their Function -- Bacterial ABC-Transporters Involved in Protein Translocation -- Bacterial Multidrug Resistance Mediated by ABC-Transporters -- Structure and Function of Osmoregulated ABC Transporters -- PART 4 -NON-MAMMALIAN EUKARYOTE ABC-TRANSPORTERS -- Inventory & Evolution of Fungal ABC Protein Genes. -- Fungal ABC Proteins in Clinical Drug Resistance & Cellular Detoxification -- Drug Resistance Mediated by ABC Transporters in Parasites of Humans -- The Plant ABC Transporter Superfamily: the Functions of a Few and Identities of Many -- PART 5-MAMMALIAN MULTIDRUG RESISTANCE ABC-TRANSPORTERS -- Solving the Problem of Multidrug Resistance: ABC Transporters in Clinical Oncology -- Multidrug Resistance Protein 1 (ABCC1) -- MRP2, the Apical Export Pump for Anionic Conjugates -- The Multidrug Resistance Proteins 3-7 -- Lipid Transport by ABC Transporters -- Role of ABCA1 in Cell Turnover and Lipid Homeostasis -- Peroxisome ABC-Transporters -- ABC-Transporters in Mitochondria -- The Transporter Associated with Antigen Processing (TAP): A Peptide Transport and Loading Complex Essential for Cellular Immune Responses -- The Sulphonylurea Receptor: an ABCC Transporter that Acts as an Ion Channel Regulator -- ABC-Transporters and Human Eye Disease -- Structure Function Analysis of CFTR.
• Publisher Details: Amsterdam Boston : Academic Press
• Publication Date: 2003
• Copyright Date: 2003
• Extent: 1 online resource (xxiii, 647 pages), illustrations (some color)
• Subjects: 572/.696; ATP-binding cassette transporters; Carrier Proteins; Transporteurs ABC; SCIENCE -- Life Sciences -- Biochemistry; ATP-binding cassette transporters; Eiwitten; Translocatie; Bacteriën; Adenosinetrifosfaat; ATP-binding cassette transporters; Electronic books
• Languages: English
• ISBNs: 0080481876; 9780080481876
• Related ISBNs: 9780123525512; 0123525519
• Notes: Note: Includes bibliographical references and index.; Note: Print version record.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.