Advances in virus research. Volume 73 (2009)

• Record Type: Book
• Further Information: Note: Edited by Karl Maramorosch, Aaron J. Shatkin, Frederick A. Murphy.
• Other Names: Maramorosch, Karl; Shatkin, Aaron J; Murphy, Frederick A
• Contents: Front Cover; Advances in Virus Research; Copyright Page; Contents; Chapter 1: Looking Back in 2009 at the Dawning of Antiviral Therapy Now 50 Years Ago: An Historical Perspective; I. Introduction; II. Thiosemicarbazones: The First Antiviral Drugs Found Active Against the Poxvirus Vaccinia Virus; III. Renaissance of the Poxvirus Inhibitors: Antiviral Drugs Against a Bioterrorist Poxvirus (Variola Virus) Attack; V. Renaissance of the Benzimidazole Derivatives: Now Turning into Lead Candidates for the Treatment of Human CMV Infections. IX. Acyclovir: The Start of the Selective Antiviral Chemotherapy Era, and Still the ``Gold Standard ́ ́ for HSV TherapyXX. New HIV Inhibitors, Targeted at Either Fusion (Enfuvirtide), Coreceptor usage (maraviroc), or Integrase (Raltegravir); Chapter 2: Use of Animal Models to Understand the Pandemic Potential of Highly Pathogenic Avian Influenza Viruses; III. Avian Influenza A Virus in Humans; B. Mouse model for H5N1 virus pathogenesis; V. Use of the Ferret Model to Study Influenza Virus Pathogenesis; A. Ferret model for human influenza A virus pathogenesis; A. Hemagglutinin cleavage site. Chapter 3: Virus Versus Host Cell Translation: Love and Hate StoriesI. Introduction; A. Editing; B. Splicing; C. Subgenomic RNA synthesis; III. Initiation of Translation; A. Cap-dependent initiation; a. In-frame initiation; b. Overlapping ORFs; 3. Shunting; G. Modification of cell factors involved in initiation; 1. Phosphorylation of eIF2alpha; 4. Cleavage of PABP; IV. Elongation of Translation; A. Frameshift; V. Termination of Translation; Acknowledgments; Index.
• Publisher Details: Amsterdam Boston : Elsevier/Academic Press
• Publication Date: 2009
• Extent: 1 online resource (vi, 177 pages), illustrations
• Subjects: 579.2; Virology; Virology -- Research; Virology -- Periodicals; Virology -- Research -- Periodicals; Virology -- Research; Virology; SCIENCE -- Life Sciences -- Biology; SCIENCE -- Life Sciences -- Microbiology; Virology; Virology -- Research; Electronic books
• Languages: English
• ISBNs: 9780080950877; 0080950876; 9780123785886
• Related ISBNs: 012378588X
• Notes: Note: Includes bibliographical references and index.; Note: Print version record.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.