Advances in immunology. Volume 69 (©1998)

• Record Type: Book
• Further Information: Note: Edited by Frank J. Dixon.
• Other Names: Dixon, Frank J (Frank James), 1920-2008
• Contents: Front Cover; Advences in Immunology, Volume 69; Copyright Page; Contents; Contributors; Chapter 1. Molecular and Cellular Events in Early Thymocyte Development; I. Introduction; II. Assays to Study Thymocyte Development in Vivo and in Vitro; III. Origin of Thymocytes: Hematopoietic Stem Cells and Early Thymocyte Progenitors; IV. Role of the Pre-T-Cell Receptor Complex in Thymocyte Development and Allelic Exclusion of the TCR ß Chain; V. Growth/Differentiation Factors in Early Thymocyte Development; VI. Transcription Factors in Early Thymocyte Development. VII. Miscellaneous Mutations and Their Roles in Early Thymocyte DevelopmentReferences; Chapter 2. Regulation of Immunoglobulin Light Chain lsotype Expression; I. Antibody Molecules and Immunoglobulin Gene Assembly; II. Allelic Exclusion of Immunoglobulin Loci; III. Tissue- and Stage-Specific Control of Immunoglobulin Light K Expression; IV. Regulation of Immunoglobulin Light Chain Gene Rearrangement; References; Chapter 3. Role of lmmunoreceptor Tyrosine-Based Activation Motif in Signal Transduction from Antigen and Fc Receptors; I. Introduction. II. Structure and Function of Immunoreceptor Tyrosine-Based Activation Motifs (ITAMs)III. ITAMs Interaction with Protein Tyrosine Kinases (PTKs); IV. ITAMs as Scaffolds for Multiple Effector Molecules; V. Involvement of ITAMs in Tolerance Induction and Immunopathology; VI. Temporal and Spatial Determinants That Coordinate Downregulation of ITAM-Induced Activation Signals; VII. Perspectives and Concluding Remarks; References; Chapter 4. The Atypical Serine Proteases of the Complement System; I. Serine Proteases in the Complement System. II. The Serine Protease Domain: Shared Features and Unique Structural Elementsof Complement ProteasesIII. Modular Structure of Complement Proteases; IV. Structure and Function of Complement Proteases; V. Summary and Perspectives; References; Chapter 5. Accessibility Control of V(D)J Recombination: Lessons from Gene Targeting; I. Introduction; II. Basic Features; III. Role of cis-Acting Elements: Trial of the Homologous Recombination Approach; IV. Targeted Mutation of trans-Regulatory Factors; V. Biological Consequences; References. Chapter 6. Interactions between the Immune System and Gene Therapy Vectors: Bidirectional Regulation of Response and ExpressionI. Introduction; II. Immunity to Vectors; III. Immunity to Gene Transfer Products; IV. Cytokine Regulation of Promoter Function; V. Immunostimulatory DNA Sequences; VI. Alteration of Immune Function by Viral Products; VII. Transfer Vectors as Enhancers of Antigen Presentation; VIII. Conclusions; References; Chapter 7. How Do Major Histocompatibility Complex Genes Influence Individual Odor and Mating Preferences?; I. Introduction.
• Publisher Details: San Diego London : Academic Press
• Publication Date: 1998
• Copyright Date: 1998
• Extent: 1 online resource (x, 462 pages), illustrations
• Subjects: 616.07/9; Immunology; Allergy and immunology -- Periodicals; Allergy and immunology; Immunity; Immunologic diseases; Immunology; Immunology -- Periodicals; MEDICAL -- Immunology; Immunology; Immunologie; Electronic books
• Languages: English
• ISBNs: 9780080578453; 0080578454; 0120224690; 9780120224692
• Notes: Note: Includes bibliographical references and index.; Note: Print version record.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.