Statistical methods for drug safety. (2015)

• Record Type: Book
• Further Information: Note: Robert D. Gibbons, Anup Amatya.
• Authors: Gibbons, Robert D, 1955-; Amatya, Anup
• Contents: Introduction; Randomized Clinical Trials; Observational Studies; The Problem of Multiple Comparisons; The Evolution of Available Data Streams; The Hierarchy of Scientific Evidence; Statistical Significance; Summary Basic Statistical Concepts; Relative Risk; Odds Ratio; Statistical Power; Maximum Likelihood Estimation; Non-Linear Regression Models; Causal Inference Multi-Level Models; Introduction; Issues Inherent in Longitudinal Data; Historical Background; Statistical Models for the Analysis of Longitudinal and/or Clustered Data Causal Inference; Introduction; Propensity Score Matching; Marginal Structural Models; Instrumental Variables; Differential Effects Analysis of Spontaneous Reports; Proportional Reporting Ratio; Bayesian Confidence Propagation Neural Network (BCPNN); Empirical Bayes Screening ; Multi-Item Gamma Poisson Shrinker; Bayesian Lasso Logistic Regression; Random-Effect Poisson Regression; Discussion Meta-Analysis; Fixed-Effect Meta-Analysis; Random-Effect Meta-Analysis; Maximum Marginal Likelihood/Empirical Bayes Method; Bayesian Meta-Analysis; Confidence Distribution Framework for Meta-Analysis; Discussion Ecological Methods; Time Series Methods; State Space Model; Change Point Analysis; Mixed-Effects Poisson Regression Model Discrete-Time Survival Models; Introduction; Discrete-Time Ordinal Regression Model; Discrete-Time Ordinal Regression Frailty Model; Illustration; Competing Risk Models; Illustration Research Synthesis; Introduction; Three-Level Mixed-Effects Regression Models Analysis of Medical Claims Data; Introduction; Administrative Claims; Observational Data; Experimental Strategies; Statistical Strategies; Illustrations; Conclusion Methods to Be Avoided; Introduction; Spontaneous Reports; Vote Counting; Simple Pooling of Studies; Including Randomized and Non-Randomized Trials in Meta-Analysis; Multiple Comparisons and Biased Reporting of Results; Immortality Time Bias Summary and Conclusions; Final Thoughts Bibliography Index
• Edition: 1st
• Publisher Details: Boca Raton : Chapman & Hall/CRC
• Publication Date: 2015
• Extent: 1 online resource, illustrations (black and white)
• Subjects: 615.7042; Pharmacoepidemiology -- Statistical methods
• Languages: English
• ISBNs: 9781466561854
• Related ISBNs: 9781466561847
• Notes: Note: Description based on CIP data; item not viewed.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.