Epigenetic cancer therapy. (2015)

• Record Type: Book
• Further Information: Note: Edited by Steven Gray.
• Editors: Gray, Steven
• Contents: 1. Introduction; 2. DNA Methylation & Hydroxymethylation in Cancer; 3. Writers, Readers, and Erasers of Epigenetic Marks; 4. MicroRNAs and Cancer; 5. Long Noncoding RNAs (lncRNAs) and Cancer; 6. Ribosomal RNA Methylation and Cancer; 7. Mining the Epigenetic Landscape: Surface Mining or Deep Underground; 8. Development of Epigenetic Targeted Therapies in Hematological Malignancies: From Serendipity to Synthetic Lethality; 9. Epigenetic Therapy in Lung Cancer and Mesothelioma; 10. Breast Cancer Epigenetics; 11. Therapeutic Applications of the Prostate Cancer Epigenome; 12. Liver Cancer (Hepatocellular Carcinoma); 13. Neuroblastoma; 14. The Epigenetics of Medulloblastoma; 15. Clinical Significance of Epigenetic Alterations in Glioblastoma; 16. Esophageal Cancer; 17. Nasopharyngeal Cancer; 18. Nutritional Epigenetic Inhibitors in the Field of Cancer: New Avenues for Chemopreventive Approaches; 19. Emerging Epigenetic Therapies – Lysine Methyltransferase/PRC Complex Inhibitors; 20. Inhibitors of Jumonji C Domain Histone Demethylases; 21. Emerging Epigenetic Therapies – Lysine Acetyltransferase Inhibitors; 22. Emerging Epigenetic Therapies – Bromodomain Ligands; 23. Clinical Trials; 24. Genetic Intratumor Heterogeneity; 25. Epigenetics Underpinning DNA Damage repair; 26. Epigenetics of Cisplatin Resistance; 27. Therapeutically Targeting Epigenetic Regulation of Cancer Stem Cells; 28. Personalized Therapy – Chemosensitivity Testing; 29. Personalized Therapy - Epigenetic Profiling as Predictors of Prognosis and Response
• Publisher Details: Amsterdam : Academic Press
• Publication Date: 2015
• Extent: 1 online resource, illustrations
• Subjects: 616.994042; Cancer -- Genetic aspects; Cancer -- Treatment; Epigenesis
• Languages: English
• ISBNs: 9780128002247
• Related ISBNs: 9780128002063
• Notes: Note: Description based on CIP data; item not viewed.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.