TRP channels as therapeutic targets : from basic science to clinical use /: from basic science to clinical use. (2015)

• Record Type: Book
• Further Information: Note: Edited by Arpad Szallasi.
• Editors: Szallasi, Arpad, 1958-
• Contents: 1. Introduction; 2. Hereditary TRP Channelopathies; 3. Changes in TRP Channel Expression in Acquired Diseases; 4. TRP Gene Polymorphism and Disease Risk; 5. Topical Capsaicin for Pain Relief; 6. TRPV1 agonist cytotoxicity for chronic pain relief; 7. Intravesical Capsaicin and Resiniferatoxin for Bladder Disorders; 8. Clinical and Preclinical Experience with TRPV1 Antagonists as Potential Analgesic Agents; 9. TRPA1 Antagonists for Pain Relief; 10. TRPA Antagonistsas Therapeutic Strategies to Reduce the Symptoms and Pathophysiology of Respiratory Disorders; 11. TRPV3 Receptors as Drug Targets: A Decade of Learning; 12. Small Molecule Agonists and Antagonists of TRPV4; 13. Potential Therapeutic Applications for TRPV4 Antagonists in Lung Disease; 14. TRPM8 as a Target for Analgesia; 15. TRP Channels: Connectivity to Cerebral Vascular Disease; 16. TRP Channels' Key Role in the Transduction of Itch; 17. Role of TRP Channels in Skin Diseases; 18. TRP Channels in Obesity/Metabolic Syndrome; 19. TRP Channels in Diabetes; 20. TRP Channels and Ca²+ Entry in Cardiac Disease; 21. The Contribution of TRP Channels to Pathophysiological Regulation of the Gastrointestinal Tract; 22. Cancer: Oncogenic and Anti-Oncogenic TRP Channels as Biomarkers and Therapeutic Targets; 23. TRP Channels in the Brain; 24. A: Mucolipidosis and TRPML Channels; 24 B: TRPML1-dependent Processes as the Therapeutic Targets; 25. TRPs in respiratory disorders: opportunities beyond TRPA1; 26. Concluding Remarks
• Publisher Details: Amsterdam : Academic Press
• Publication Date: 2015
• Extent: 1 online resource, illustrations
• Subjects: 572.696; TRP channels; Drug targeting
• Languages: English
• ISBNs: 9780124200791
• Related ISBNs: 9780124200241
• Notes: Note: Description based on CIP data; item not viewed.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.