The toxicology and biochemistry of insecticides. (2015)

• Record Type: Book
• Further Information: Note: Simon J. Yu.
• Authors: Yu, Simon J
• Contents: Preface to the Second Edition Preface to the First Edition Author Need for Pesticides and Their Pattern of Use Introduction Need for Pesticides Food Production World Health Status Pattern of Use Pesticide Economics References Formulation of Pesticides Introduction Types of Formulation Dusts Wettable Powders Emulsifiable Concentrates Suspendable Concentrates or Flowables Water-Soluble Powders Solutions Granules Water-Dispersible Granules Ultralow-Volume Formulations Aerosols Controlled-Release Formulations Baits Nonpesticidal Ingredients of Formulations Solvents Diluents Surfactants Disposal of Pesticide Containers Pesticide Application Equipment References Pesticide Laws and Regulations Introduction Federal Insecticide, Fungicide, and Rodenticide Act Registration of Pesticides Classification of Pesticides and Certification of Applicators Other Provisions of FIFRA Pesticide Categories Federal Food, Drug, and Cosmetic Act Tolerance Basis for Tolerance Food Quality Protection Act State Laws Enforcement References Classification of Insecticides Introduction Classification of Insecticides Chlorinated Hydrocarbon Insecticides Organophosphates Carbamates Pyrethroids Botanical Insecticides Insect Growth Regulators Neonicotinoids Formamidines Microbial Insecticides Fumigants Inorganic Insecticides Miscellaneous Insecticide Classes Acaricides Insect Repellents References Evaluation of Toxicity Introduction Testing Procedures Tests with Insects Topical Application Injection Method Dipping Method Contact Method (Residual Exposure Method) Fumigation Method Feeding Method Tests with Higher Animals Acute Toxicity Tests Subacute Toxicity and Chronic Toxicity Tests Probit Analysis Source of Variability in Dose–Response Tests Age Sex Rearing Temperature Food Supply Population Density Illumination Use of LDP Lines Appendix References Uptake of Insecticides Introduction Penetration of Insecticides through the Insect Cuticle Structure of Insect Cuticle Movement of Insecticides through the Cuticle Site of Entry Factors Affecting Cuticular Penetration Rates Metabolism of Insecticides in the Cuticle Entry via the Mouth Uptake via the Spiracles References Mode of Action of Insecticides Introduction Insecticides Affecting Voltage-Gated Sodium Channels Background Mode of Action of the DDT Group, Pyrethroids, Indoxacarb, Sabadilla, and Metaflumizone Insecticides Affecting Ryanodine Receptors Insecticides Inhibiting Acetylcholinesterase Background Mode of Action of Organophosphorus and Carbamate Insecticides Insecticides Interfering with Chloride Channels GABA-Gated Chloride Channels Glutamate-Gated Chloride Channels Insecticides That Bind to Nicotinic Acetylcholine Receptors Insecticides Affecting Octopamine Receptors Insecticides Interfering with Respiration Inhibitors of the Mitochondrial Electron Transport System Inhibitors of Oxidative Phosphorylation Insecticides Disrupting Insect Midgut Membranes Bacillus thuringiensis Bacillus sphaericus Mode of Action of Baculovirus Insecticides Insecticides Affecting Chitin Biosynthesis or Cuticle Sclerotization Insecticides Acting as Juvenile Hormone Mimics Insecticides Acting as Ecdysone Agonists or Blocking Molting Hormone Activity Insecticides Causing Protein Degradation and Necrotic Cell Death Insecticides Abrading or Disrupting Insect Cuticle Insecticides Acting as Selective Feeding Blockers Insecticides Causing Suffocation Mode of Action of Acaricides Acaricides Interfering with Respiration Acaricides Interfering with Growth and Development Acaricides Acting as Neurotoxins Mode of Action of Insect Repellents References Principles of Pesticide Metabolism Introduction Phase I Reactions Oxidation Hydrolysis Reduction Phase II Reactions Glucose Conjugation Glucuronic Acid Conjugation Sulfate Conjugation Phosphate Conjugation Amino Acid Conjugation Glutathione Conjugation Metabolic Systems in Plants Metabolic Pathways of Selected Insecticides Carbamates Organophosphates Pyrethroids Chlorinated Hydrocarbons Benzoylphenylureas Juvenoids Neonicotinoids Formamidines Amidinohydrazones Phenylpyrazoles Thiadiazines Triazines Quinazolines Organotins Microbial Insecticides Diacylhydrazines Nereistoxin Analogs Thiocarbamates Organosulfurs Pyrazoles Phthalic Acid Diamides Anthranilic Diamides Tetronic Acids Dichloropropenyl Ethers References Species Differences and Other Phenomena Associated with the Metabolism of Xenobiotics Introduction Species Differences in Detoxification Enzyme Activity Examples of Differences Evolution of Species Differences in Detoxification Effect of Age and Sex on Enzyme Activity Specificity of Detoxification Enzymes Selective Toxicity Synergism and Antagonism Enzyme Induction Induction of Detoxification Enzymes Enzyme Induction as Detoxification Mechanism Insecticide Resistance References Insecticide Resistance Introduction Genetics of Resistance Preadaptation Gene Frequency Dominance and Number of Genes Reversion of Resistance Mechanisms of Resistance Behavioral Resistance Physiological Resistance Interaction Phenomena Cross-Resistance and Multiple Resistance Interaction of Resistance Factors Fitness Costs of Insecticide Resistance Rate of Development of Resistance Frequency of R Alleles Dominance of R Alleles Generation Turnover Population Mobility Persistence of Pesticide Residues Selection Pressure Pattern of Resistance Development Management of Resistance Reducing Resistance Gene Frequency Use of Insecticide Mixtures and Rotations Use of Ins
• Edition: Second edition
• Publisher Details: Boca Raton : CRC Press
• Publication Date: 2015
• Extent: 1 online resource, illustrations
• Subjects: 632.9517; Insecticides; Insecticides -- Toxicology; Insecticides -- Physiological effect
• Languages: English
• ISBNs: 9781482210613
• Notes: Note: Includes bibliographical references.; Note: Description based on CIP data; resource not viewed.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.