Clinical trial biostatistics and biopharmaceutical applications. (2014)

• Record Type: Book
• Further Information: Note: Editors, Walter R. Young, Ding-Geng (Din) Chen.
• Editors: Young, Walter R; Chen, Ding-Geng
• Contents: Emerging Issues in Clinical Trial Design and Analysis; Emerging Challenges of Clinical Trial Methodologies in Regulatory Applications H.M. James Hung and Sue-Jane Wang; Review of RandomizationMethods in Clinical Trials Vance W. Berger and William C. Grant; First Dose Ranging Clinical Trial Design: More Doses? Or a Wider Range? Guojun Yuan and Naitee Ting; Thorough QT/QTc Clinical Trials Yi Tsong; Controversial (Unresolved) Issues in Noninferiority Trials Brian L. Wiens Adaptive Clinical Trials; Adaptive Designs in Drug Development Sue-Jane Wang and H.M. James Hung; Optimizing Group-Sequential Designs with Focus on Adaptability: Implications of Nonproportional Hazards in Clinical Trials Edward Lakatos; Group Sequential Design in R Keaven M. Anderson Clinical Trials in Oncology; Issues in the Design and Analysis of Oncology Clinical Trials Stephanie Green; Competing Risks and Their Applications in Cancer Clinical Trials Chen Hu, James J. Dignam, and Ding-Geng (Din) Chen; Dose Finding with Escalation with Overdose Control in Cancer Clinical Trials André Rogatko and Mourad Tighiouart; Interval-Censored Time-to-Event Data and Their Applications in Clinical Trials Ling Ma, Yanqin Feng, Ding-Geng (Din) Chen, and Jianguo Sun Multiple Comparisons in Clinical Trials; Introduction to Multiple Test Problems, with Applications to Adaptive Designs Jeff Maca, Frank Bretz, and Willi Maurer; Graphical Approaches to Multiple Testing Frank Bretz, Willi Maurer, and Jeff Maca; Pairwise Comparisons with Binary Responses: Multiplicity-Adjusted P -Values and Simultaneous Confidence Intervals Bernhard Klingenberg and Faraz Rahman; Comparative Study of FiveWeighted Parametric Multiple Testing Methods for Correlated Multiple Endpoints in Clinical Trials Changchun Xie, Xuewen Lu, and Ding-Geng (Din) Chen Clinical Trials in the Genomic Era; Statistical Analysis of Biomarkers from Omics Technologies Herbert Pang and Hongyu Zhao; Understanding Therapeutic Pathways via Biomarkers and Other Uses of Biomarkers in Clinical Studies Michael D. Hale and Scott D. Patterson; Statistical Evaluation of Surrogate Endpoints in Clinical Studies Geert Molenberghs, Ariel Alonso Abad, Wim Van der Elst, Tomasz Burzykowski, and Marc Buyse Index
• Edition: 1st
• Publisher Details: Boca Raton : Chapman & Hall/CRC
• Publication Date: 2014
• Extent: 1 online resource, illustrations (black and white)
• Subjects: 610.727; Biometry -- Methodology; Biopharmaceutics -- Methodology; Clinical trials
• Languages: English
• ISBNs: 9781482212198
• Related ISBNs: 9781482212181
• Notes: Note: Includes bibliographical references and index.; Note: Description based on CIP data; item not viewed.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.