Mixed effects models for the population approach : models, tasks, methods and tools /: models, tasks, methods and tools. (2014)
- Record Type:
- Book
- Title:
- Mixed effects models for the population approach : models, tasks, methods and tools /: models, tasks, methods and tools. (2014)
- Main Title:
- Mixed effects models for the population approach : models, tasks, methods and tools
- Further Information:
- Note: Marc Lavielle.
- Authors:
- Lavielle, Marc
- Contents:
- Introduction and Preliminary Concepts; Overview; The population approach; About models; Tasks, methods and tools; Contents of the book Mixed Effects Models vs Hierarchical Models ; From linear models to nonlinear mixed effects models; From nonlinear mixed effects models to hierarchical models; From generalized mixed models to hierarchical models What Is a Model? A Joint Probability Distribution! ; Introduction and notation; An illustrative example; Using a model for executing tasks; Implementing hierarchical models with Mlxtran Defining Models ; Modeling Observations ; Introduction; Continuous data models; Models for count data; Models for categorical data; Models for time-to-event data; Joint models Modeling the Individual Parameters ; Introduction ; Gaussian models; Models with covariates; Extensions to multivariate distributions; Additional levels of variability; Different mathematical representations and implementations of the same model Extensions ; Mixture models; Markov models; Stochastic differential equation-based models Using Models ; Tasks and Methods ; Introduction; Estimation; Model evaluation Examples ; Body weight curves in a toxicity study; Joint PKPD modeling of warfarin data; Gene expression in single cells Algorithms ; Introduction; The SAEM algorithm for estimating population parameters; The Metropolis-Hastings algorithm for simulating the individual parameters; Estimation of the observed Fisher information matrix; Estimation of the log-likelihood;Introduction and Preliminary Concepts; Overview; The population approach; About models; Tasks, methods and tools; Contents of the book Mixed Effects Models vs Hierarchical Models ; From linear models to nonlinear mixed effects models; From nonlinear mixed effects models to hierarchical models; From generalized mixed models to hierarchical models What Is a Model? A Joint Probability Distribution! ; Introduction and notation; An illustrative example; Using a model for executing tasks; Implementing hierarchical models with Mlxtran Defining Models ; Modeling Observations ; Introduction; Continuous data models; Models for count data; Models for categorical data; Models for time-to-event data; Joint models Modeling the Individual Parameters ; Introduction ; Gaussian models; Models with covariates; Extensions to multivariate distributions; Additional levels of variability; Different mathematical representations and implementations of the same model Extensions ; Mixture models; Markov models; Stochastic differential equation-based models Using Models ; Tasks and Methods ; Introduction; Estimation; Model evaluation Examples ; Body weight curves in a toxicity study; Joint PKPD modeling of warfarin data; Gene expression in single cells Algorithms ; Introduction; The SAEM algorithm for estimating population parameters; The Metropolis-Hastings algorithm for simulating the individual parameters; Estimation of the observed Fisher information matrix; Estimation of the log-likelihood; Examples of calculating the log-likelihood and it derivatives; Automatic construction of visual predictive checks Appendices ; The Individual Approach; Some Useful Results; Introduction to Pharmacokinetics Modeling; Tools Bibliography Glossary Index … (more)
- Edition:
- 1st
- Publisher Details:
- Boca Raton : Chapman & Hall/CRC
- Publication Date:
- 2014
- Extent:
- 1 online resource, illustrations (black and white)
- Subjects:
- 001.422
Multilevel models (Statistics)
Biometry
Population -- Statistics - Languages:
- English
- ISBNs:
- 9781482226515
- Related ISBNs:
- 9781482226508
- Notes:
- Note: Includes bibliographical references and index.
Note: Description based on CIP data; item not viewed. - Access Rights:
- Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
- Access Usage:
- Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library HMNTS - ELD.DS.143897
- Ingest File:
- 02_179.xml