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Subject Hyperphosphatemia -- NaPi2b -- NaPi2b inhibitor -- Gut-selective -- Bioavailability

1. Design, synthesis and biological evaluation of novel 1H-pyrazole-4-carbonyl-4, 5, 6, 7-tetrahydrobenzo [b]thiophene derivatives as gut-selective NaPi2b inhibitors. (1st March 2022)

Authors:
Ushiki, Yasunobu; Kawabe, Kenichi; Yamamoto-Okada, Kumiko; Uneuchi, Fumito; Asanuma, Yuta; Yamaguchi, Chitose; Ohta, Hiroshi; Shibata, Tsuyoshi; Abe, Tomohiro; Okumura-Kitajima, Lisa; Kosai, Yuki; Endo, Mayumi; Otake, Katsumasa; Munetomo, Eiji; Takahashi, Teisuke; Kakinuma, Hiroyuki
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 59(2022)
Page Start:
Record Type:
Journal Article
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Available online (eLD content is only available in our Reading Rooms) ↗

2. Design, synthesis and biological evaluation of novel indole derivatives as gut-selective NaPi2b inhibitors. (15th July 2022)

Authors:
Ushiki, Yasunobu; Kawabe, Kenichi; Yamamoto-Okada, Kumiko; Uneuchi, Fumito; Asanuma, Yuta; Yamaguchi, Chitose; Ohta, Hiroshi; Shibata, Tsuyoshi; Abe, Tomohiro; Okumura-Kitajima, Lisa; Kosai, Yuki; Endo, Mayumi; Otake, Katsumasa; Munetomo, Eiji; Takahashi, Teisuke; Kakinuma, Hiroyuki
Journal:
Bioorganic & medicinal chemistry
Issue:
Volume 66(2022)
Page Start:
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗

3. Design, synthesis and biological evaluation of novel pyridine derivatives as gut-selective NaPi2b inhibitors. (1st June 2022)

Authors:
Ushiki, Yasunobu; Kawabe, Kenichi; Yamamoto-Okada, Kumiko; Uneuchi, Fumito; Asanuma, Yuta; Yamaguchi, Chitose; Ohta, Hiroshi; Shibata, Tsuyoshi; Abe, Tomohiro; Okumura-Kitajima, Lisa; Kosai, Yuki; Endo, Mayumi; Otake, Katsumasa; Munetomo, Eiji; Takahashi, Teisuke; Kakinuma, Hiroyuki
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 65(2022)
Page Start:
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗

  • Hyperphosphatemia -- NaPi2b -- NaPi2b inhibitor -- Gut-selective -- Bioavailability 3