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Author/Creator Zigler, Melanie C.

1. Dietary rapamycin supplementation reverses age‐related vascular dysfunction and oxidative stress, while modulating nutrient‐sensing, cell cycle, and senescence pathways. Issue 1 (22nd September 2016)

Authors:
Lesniewski, Lisa A.; Seals, Douglas R.; Walker, Ashley E.; Henson, Grant D.; Blimline, Mark W.; Trott, Daniel W.; Bosshardt, Gary C.; LaRocca, Thomas J.; Lawson, Brooke R.; Zigler, Melanie C.; Donato, Anthony J.
Journal:
Aging cell
Issue:
Volume 16:Issue 1(2017)
Page Start:
17
Record Type:
Journal Article
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Available online (eLD content is only available in our Reading Rooms) ↗

2. Gut Microbiome-Derived Metabolite Trimethylamine N-Oxide Induces Aortic Stiffening and Increases Systolic Blood Pressure With Aging in Mice and Humans. Issue 2 (10th May 2021)

Authors:
Brunt, Vienna E.; Casso, Abigail G.; Gioscia-Ryan, Rachel A.; Sapinsley, Zachary J.; Ziemba, Brian P.; Clayton, Zachary S.; Bazzoni, Amy E.; VanDongen, Nicholas S.; Richey, James J.; Hutton, David A.; Zigler, Melanie C.; Neilson, Andrew P.; Davy, Kevin P.; Seals, Douglas R.
Journal:
Hypertension
Issue:
Volume 78:Issue 2(2021)
Page Start:
499
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗

3. Lifelong voluntary aerobic exercise prevents age‐ and Western diet‐ induced vascular dysfunction, mitochondrial oxidative stress and inflammation in mice. (28th October 2020)

Authors:
Gioscia‐Ryan, Rachel A.; Clayton, Zachary S.; Zigler, Melanie C.; Richey, James J.; Cuevas, Lauren M.; Rossman, Matthew J.; Battson, Micah L.; Ziemba, Brian P.; Hutton, David A.; VanDongen, Nicholas S.; Seals, Douglas R.
Journal:
Journal of physiology
Issue:
Volume 599:Number 3(2021)
Page Start:
911
Record Type:
Journal Article
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Available online (eLD content is only available in our Reading Rooms) ↗

6. Short‐term interleukin‐37 treatment improves vascular endothelial function, endurance exercise capacity, and whole‐body glucose metabolism in old mice. Issue 1 (21st November 2019)

Authors:
Ballak, Dov B.; Brunt, Vienna E.; Sapinsley, Zachary J.; Ziemba, Brian P.; Richey, James J.; Zigler, Melanie C.; Johnson, Lawrence C.; Gioscia‐Ryan, Rachel A.; Culp‐Hill, Rachel; Eisenmesser, Elan Z.; D'Alessandro, Angelo; Dinarello, Charles A.; Seals, Douglas R.
Journal:
Aging cell
Issue:
Volume 19:Issue 1(2020)
Page Start:
n/a
Record Type:
Journal Article
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Available online (eLD content is only available in our Reading Rooms) ↗

7. Suppression of the gut microbiome ameliorates age‐related arterial dysfunction and oxidative stress in mice. (27th February 2019)

Authors:
Brunt, Vienna E.; Gioscia‐Ryan, Rachel A.; Richey, James J.; Zigler, Melanie C.; Cuevas, Lauren M.; Gonzalez, Antonio; Vázquez‐Baeza, Yoshiki; Battson, Micah L.; Smithson, Andrew T.; Gilley, Andrew D.; Ackermann, Gail; Neilson, Andrew P.; Weir, Tiffany; Davy, Kevin P.; Knight, Rob; Seals, Douglas R.
Journal:
Journal of physiology
Issue:
Volume 597:Number 9(2019)
Page Start:
2361
Record Type:
Journal Article
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8. Trimethylamine-N-Oxide Promotes Age-Related Vascular Oxidative Stress and Endothelial Dysfunction in Mice and Healthy Humans. Issue 1 (July 2020)

Authors:
Brunt, Vienna E.; Gioscia-Ryan, Rachel A.; Casso, Abigail G.; VanDongen, Nicholas S.; Ziemba, Brian P.; Sapinsley, Zachary J.; Richey, James J.; Zigler, Melanie C.; Neilson, Andrew P.; Davy, Kevin P.; Seals, Douglas R.
Journal:
Hypertension
Issue:
Volume 76:Issue 1(2020)
Page Start:
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗