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Author/Creator Wu, Dauh-Rurng

1. Annulation reaction enables the identification of an exocyclic amide tricyclic chemotype as retinoic acid Receptor-Related orphan receptor gamma (RORγ/RORc) inverse agonists. Issue 19 (1st October 2020)

Authors:
Marcoux, David; Bertrand, Myra Beaudoin; Weigelt, Carolyn A.; Yip, Shiuhang; Galella, Michael; Park, Hyunsoo; Wu, Dauh-Rurng; Wang, Jinhong; Yarde, Melissa; Cvijic, Mary Ellen; Li, Sha; Hynes, John; Tino, Joseph A.; Zhao, Qihong; Dhar, T.G. Murali
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 30:Issue 19(2020)
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Journal Article
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2. BMS-871: A novel orally active pan-Notch inhibitor as an anticancer agent. Issue 9 (1st May 2015)

Authors:
Shan, Weifang; Balog, Aaron; Quesnelle, Claude; Gill, Patrice; Han, Wen-Ching; Norris, Derek; Mandal, Sunilkumar; Thiruvenkadam, Raja; Gona, Kiran Babu; Thiyagarajan, Kamalraj; Kandula, Sathiah; McGlinchey, Kelly; Menard, Krista; Wen, Mei-Li; Rose, Anne; White, Ronald; Guarino, Victor; Shen, Ding...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 25:Issue 9(2015)
Page Start:
1905
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Journal Article
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3. BMS-871: A novel orally active pan-Notch inhibitor as an anticancer agent. Issue 9 (1st May 2015)

Authors:
Shan, Weifang; Balog, Aaron; Quesnelle, Claude; Gill, Patrice; Han, Wen-Ching; Norris, Derek; Mandal, Sunilkumar; Thiruvenkadam, Raja; Gona, Kiran Babu; Thiyagarajan, Kamalraj; Kandula, Sathiah; McGlinchey, Kelly; Menard, Krista; Wen, Mei-Li; Rose, Anne; White, Ronald; Guarino, Victor; Shen, Ding...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 25:Issue 9(2015)
Page Start:
1905
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Journal Article
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4. Discovery of (3S, 4S)-3-methyl-3-(4-fluorophenyl)-4-(4-(1, 1, 1, 3, 3, 3-hexafluoro-2-hydroxyprop-2-yl)phenyl)pyrrolidines as novel RORγt inverse agonists. Issue 17 (1st September 2020)

Authors:
Jiang, Bin; Duan, James J.-W.; Stachura, Sylwia; Karmakar, Ananta; Hemagiri, Hemalatha; Raut, Dhanya Kumar; Gupta, Arun Kumar; Weigelt, Carolyn A.; Khan, Javed; Sack, John S.; Wu, Dauh-Rurng; Yarde, Melissa; Shen, Ding-Ren; Galella, Michael A.; Mathur, Arvind; Zhao, Qihong; Salter-Cid, Luisa M.; ...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 30:Issue 17(2020)
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5. Discovery of BMS-961955, an allosteric inhibitor of the hepatitis C virus NS5B polymerase. Issue 15 (1st August 2017)

Authors:
Zheng, Barbara Zhizhen; D'Andrea, Stanley V.; Hanumegowda, Umesh; Knipe, Jay O.; Mosure, Kathy; Zhuo, Xiaoliang; Lemm, Julie A.; Liu, Mengping; Rigat, Karen L.; Wang, Ying-Kai; Fang, Hua; Poronsky, Chris; Cutrone, Jingfang; Wu, Dauh-Rurng; Arunachalam, Pirama Nayagam; Balapragalathan, T.J.; Arumu...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 27:Issue 15(2017)
Page Start:
3294
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Journal Article
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6. Enantioselective synthesis of BMS-911278: a triple reuptake inhibitor. Issue 1 (15th January 2017)

Authors:
Li, Jianqing; Smith, Daniel; Krishnananthan, Subramaniam; Wu, Dauh-Rurng; Sun, Dawn; Li, Peng; Ryan, Kristen; Hu, Min; Cui, Wenge; Naginskaya, Jennifer; Liu, Shuang; Lobben, Paul C.; Ng, Alicia T.; Olson, Richard; Mathur, Arvind
Journal:
Tetrahedron, asymmetry
Issue:
Volume 28:Issue 1(2017)
Page Start:
196
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Journal Article
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7. Identification of bicyclic hexafluoroisopropyl alcohol sulfonamides as retinoic acid receptor-related orphan receptor gamma (RORγ/RORc) inverse agonists. Employing structure-based drug design to improve pregnane X receptor (PXR) selectivity. Issue 2 (15th January 2018)

Authors:
Gong, Hua; Weinstein, David S.; Lu, Zhonghui; Duan, James J.-W.; Stachura, Sylwia; Haque, Lauren; Karmakar, Ananta; Hemagiri, Hemalatha; Raut, Dhanya Kumar; Gupta, Arun Kumar; Khan, Javed; Camac, Dan; Sack, John S.; Pudzianowski, Andrew; Wu, Dauh-Rurng; Yarde, Melissa; Shen, Ding-Ren; Borowski, V...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 28:Issue 2(2018)
Page Start:
85
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Journal Article
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8. Identification of potent tricyclic prodrug S1P1 receptor modulators12. Issue 4 (1st December 2016)

Authors:
Marcoux, David; Xiao, Hai-Yun; Murali Dhar, T. G.; Xie, Jenny; Lehman-McKeeman, Lois D.; Wu, Dauh-Rurng; Dabros, Marta; Yang, Xiaoxia; Taylor, Tracy L.; Zhou, Xia D.; Heimrich, Elizabeth M.; Thomas, Rochelle; McIntyre, Kim W.; Shi, Hong; Levesque, Paul C.; Sun, Huadong; Yang, Zheng; Marino, Antho...
Journal:
MedChemComm
Issue:
Volume 8:Issue 4(2017)
Page Start:
725
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Journal Article
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9. Identification of potent, selective and orally bioavailable phenyl ((R)-3-phenylpyrrolidin-3-yl)sulfone analogues as RORγt inverse agonists. Issue 16 (15th August 2019)

Authors:
Lu, Zhonghui; Duan, James J.-W.; Xiao, Haiyun; Neels, James; Wu, Dauh-Rurng; Weigelt, Carolyn A.; Sack, John S.; Khan, Javed; Ruzanov, Max; An, Yongmi; Yarde, Melissa; Karmakar, Ananta; Vishwakrishnan, Sureshbabu; Baratam, Venkata; Shankarappa, Harisha; Vanteru, Sridhar; Babu, Venkatesh; Basha, M...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 29:Issue 16(2019)
Page Start:
2265
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Journal Article
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10. Tricyclic sulfones as potent, selective and efficacious RORγt inverse agonists – Exploring C6 and C8 SAR using late-stage functionalization. Issue 23 (1st December 2020)

Authors:
Shi, Qing; Xiao, Zili; Yang, Michael G.; Marcoux, David; Cherney, Robert J.; Yip, Shiuhang; Li, Peng; Wu, Dauh-Rurng; Weigelt, Carolyn A.; Sack, John; Khan, Javed; Ruzanov, Max; Wang, Jinhong; Yarde, Melissa; Ellen Cvijic, Mary; Li, Sha; Shuster, David J.; Xie, Jenny; Sherry, Tara; Obermeier, Mary
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 30:Issue 23(2020)
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Journal Article
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