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Author/Creator Westphal, Ryan

1. Biochemical and behavioral effects of PDE10A inhibitors: Relationship to target site occupancy. (March 2016)

Authors:
Li, Yu-Wen; Seager, Matthew A.; Wojcik, Trevor; Heman, Karen; Molski, Thaddeus F.; Fernandes, Alda; Langdon, Shaun; Pendri, Annapurna; Gerritz, Samuel; Tian, Yuan; Hong, Yang; Gallagher, Lizbeth; Merritt, James R.; Zhang, Chongwu; Westphal, Ryan; Zaczek, Robert; Macor, John E.; Bronson, Joanne J....
Journal:
Neuropharmacology
Issue:
Volume 102(2016)
Page Start:
121
Record Type:
Journal Article
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2. Biochemical and behavioral effects of PDE10A inhibitors: Relationship to target site occupancy. (March 2016)

Authors:
Li, Yu-Wen; Seager, Matthew A.; Wojcik, Trevor; Heman, Karen; Molski, Thaddeus F.; Fernandes, Alda; Langdon, Shaun; Pendri, Annapurna; Gerritz, Samuel; Tian, Yuan; Hong, Yang; Gallagher, Lizbeth; Merritt, James R.; Zhang, Chongwu; Westphal, Ryan; Zaczek, Robert; Macor, John E.; Bronson, Joanne J....
Journal:
Neuropharmacology
Issue:
Volume 102(2016)
Page Start:
121
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗

3. Design, synthesis, and evaluation of phenylglycinols and phenyl amines as agonists of GPR88. Issue 7 (1st April 2015)

Authors:
Dzierba, Carolyn D.; Bi, Yingzhi; Dasgupta, Bireshwar; Hartz, Richard A.; Ahuja, Vijay; Cianchetta, Giovanni; Kumi, Godwin; Dong, Li; Aleem, Saadat; Fink, Cynthia; Garcia, Yudith; Green, Michael; Han, Jianxin; Kwon, Soojin; Qiao, Ying; Wang, Jiancheng; Zhang, Yulian; Liu, Ying; Zipp, Greg; Liang,...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 25:Issue 7(2015)
Page Start:
1448
Record Type:
Journal Article
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4. Difluorocyclobutylacetylenes as positive allosteric modulators of mGluR5 with reduced bioactivation potential. Issue 24 (15th December 2016)

Authors:
Degnan, Andrew P.; Maxwell, Darrell; Balakrishnan, Anand; Brown, Jeffrey M.; Easton, Amy; Gulianello, Michael; Hanumegowda, Umesh; Hill-Drzewi, Melissa; Miller, Regina; Santone, Kenneth S.; Senapati, Arun; Shields, Eric E.; Sivarao, Digavalli V.; Westphal, Ryan; Whiterock, Valerie J.; Zhuo, Xiaol...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 26:Issue 24(2016)
Page Start:
5871
Record Type:
Journal Article
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5. Oxazolidinone-based allosteric modulators of mGluR5: Defining molecular switches to create a pharmacological tool box. Issue 17 (1st September 2016)

Authors:
Huang, Hong; Degnan, Andrew P.; Balakrishnan, Anand; Easton, Amy; Gulianello, Michael; Huang, Yanling; Matchett, Michele; Mattson, Gail; Miller, Regina; Santone, Kenneth S.; Senapati, Arun; Shields, Eric E.; Sivarao, Digavalli V.; Snyder, Lawrence B.; Westphal, Ryan; Whiterock, Valerie J.; Yang, ...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 26:Issue 17(2016)
Page Start:
4165
Record Type:
Journal Article
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6. The discovery of VU0652957 (VU2957, Valiglurax): SAR and DMPK challenges en route to an mGlu4 PAM development candidate. Issue 2 (15th January 2019)

Authors:
Panarese, Joseph D.; Engers, Darren W.; Wu, Yong-Jin; Guernon, Jason M.; Chun, Aspen; Gregro, Alison R.; Bender, Aaron M.; Capstick, Rory A.; Wieting, Joshua M.; Bronson, Joanne J.; Macor, John E.; Westphal, Ryan; Soars, Matthew; Engers, Julie E.; Felts, Andrew S.; Rodriguez, Alice L.; Emmitte, K...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 29:Issue 2(2019)
Page Start:
342
Record Type:
Journal Article
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Available online (eLD content is only available in our Reading Rooms) ↗