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You searched for: Author/Creator Weng, Shanshan- Weng, Shanshan [remove] 4
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- GEC Gastroesophageal cancer -- HER-2 Human epidermal growth factor receptor-2 -- PD1 / PD-L1 programmed cell death protein1/ programmed death ligand 1 -- CTLA4 cytotoxic T-lymphocyte-associated protein 4 -- Lag-3 Lymphocyte activation gene-3 -- OS overall survival -- TOGA Trastuzumab for Gastric Cancer study -- TME tumor micro-environment -- FDA food and Drug Administration -- TMB tumor mutational burden -- MSI-H microsatellite instability-high -- dMMR mismatch repair deficient -- TILs tumor- infiltrating lymphocytes -- INF-γ interferon-γ -- EBV Epstein–Barr Virus -- ADCC antibody-dependent cellular cytotoxicity -- NK Natural Killer -- TAMs tumor-associated macrophages -- BsAb bispecific antibody -- mAb monoclonal antibody -- ORR objective response rate -- DCR disease control rate -- SD stable disease -- mPFS median progression-free survival -- NGS next-generation sequencing -- AEs adverse events -- RR response rate -- ORR Overall response rate -- T-DXd Trastuzumab deruxtecan -- MMAE monomethyl auristatin E -- pCR pathologic Complete Response -- MPR major pathologic response -- CPS combined positive score -- CAFs cancer-associated fibroblasts -- TSR Tumor stromal ratio 1
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