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You searched for: Author/Creator Wallis, N.

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1. A combination vertical inhibition approach with inhibitors of SHP2 and ERK provides improved activity in KRAS-mutant pancreatic and colorectal cancer models. (October 2022)

2. Combined inhibition of SHP2 and ERK enhances anti-tumour effects in preclinical models. (October 2020)

4. Large-scale implementation of pooled RNA extraction and RT-PCR for SARS-CoV-2 detection. (September 2020)

6. The clinical candidate, ASTX029, is a novel, dual mechanism ERK1/2 inhibitor and has potent activity in MAPK-activated cancer cell lines and in vivo tumor models. (October 2020)