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You searched for: Author/Creator Van Rompay, A.R.- Van Rompay, A.R. [remove] 17
- Toxicology -- Periodicals 17
- 615.9 12
- Toxicity testing -- In vitro -- Periodicals 12
- 363.179 5
- BCOP Bovine Corneal Opacity and Permeability -- BLR between laboratory reproducibility -- C classified -- CAS RN Chemical Abstracts Service Registry Number -- Cat 1 UN GHS classification for chemicals causing irreversible effects on the eye/serious damage to the eye -- Cat 2 UN GHS classification for chemicals causing reversible effects on the eye/eye irritation, sub-categorised in 2A (irritant to eyes, eye effects are not fully reversible within 7 days of observation) and 2B (mildly irritant to eyes, eye effects fully reversible within 7 days of observation) -- CC Conjunctival Chemosis -- CI confidence interval -- CM Cytosensor Microphysiometer -- CO Corneal Opacity -- Conj CR and/or CC -- CR Conjunctival Redness -- CRL Charles River Laboratories -- DRD Draize eye test Reference Database -- EIT Eye Irritation Test -- EITL Eye Irritation Testing of Liquids -- EITS Eye Irritation Testing of Solids -- EURL ECVAM European Union Reference Laboratory for Alternatives to Animal Testing -- HCE Human Corneal Epithelium -- HPLC/UPLC High/Ultra Performance Liquid Chromatography -- ICCVAM Interagency Coordinating Committee on the Validation of Alternative Methods -- ICE Isolated Chicken Eye -- IR Iritis -- LO L'Oréal -- MTT 3-[4, 5-dimethylthiazole-2-yl]-2, 5-diphenyltetrazolium bromide -- NgC negative control -- NC not classified -- No Cat chemicals not classified for serious eye damage/eye irritation under UN GHS/EU CLP -- NSC non-specific colour -- NSCkilled non-specific colour on killed tissues -- NSMTT non-specific reduction of MTT -- OD optical density -- OECD Organisation for Economic Co-operation and Development -- PC positive control -- PBS phosphate-buffered saline -- pers persistence -- RhCE Reconstructed human Cornea-like Epithelium -- RhT Reconstructed human Tissue -- SCNM study criteria not met -- STE short-time exposure -- S.O.P. Standard Operating Procedure -- TG Test Guideline -- UN GHS United Nations Globally Harmonized System of Classification and Labelling of Chemicals -- VITO Flemish Institute for Technological Research -- VMG Validation Management Group -- VRM validation reference method -- WLR within laboratory reproducibility 2
- CON4EI -- Ocular irritation -- Reference chemicals -- Draize rabbit eye test -- UN GHS categories 2
- Ocular toxicity -- SkinEthic HCE -- Reconstructed human corneal tissue -- Validation -- Reproducibility -- Predictive capacity 2
- ALT4EI ALTernatives for Eye Irritation -- BCOP Bovine Corneal Opacity and Permeability -- CAS RN Chemical Abstracts Service Registry Number -- Cat. 1 UN GHS/EU CLP classification for chemicals causing irreversible effects on the eye/serious damage to the eye -- Cat. 2 UN GHS/EU CLP classification for chemicals causing reversible effects on the eye/eye irritation, sub-categorised in 2A (irritant to eyes, eye effects are not fully reversible within 7 days of observation) and 2B (mildly irritant to eyes, eye effects fully reversible within 7 days of observation) -- CEFIC European Chemical Industry Council -- CC Conjunctival Chemosis -- CO Corneal Opacity -- CR Conjunctival Redness -- CON4EI CONsortium for in vitro Eye Irritation testing strategy -- DRD Draize eye test Reference Database -- EU CLP European Union Regulation on Classification, Labelling and Packaging of chemicals implementing UN GHS in the EU -- FNR False Negative Rate -- FPR False Positive Rate -- IATA Integrated Approach on Testing and Assessment -- IR iritis -- IRE Isolated Rabbit Eye -- IVIS In Vitro Irritation Score -- LIS LLBO Irritation Score -- LLBO Laser Light-Based Opacitometer -- NC Negative Control -- No Cat Chemicals not classified for serious eye damage or eye irritation under UN GHS/EU CLP -- NPCM No Stand-alone Prediction can be made -- OD Optical density -- OECD Organisation for Economic Co-operation and Development -- PC Positive Control -- pers. Persistence -- RhCE Reconstructed human Cornea-like Epithelium -- STE Short Time Exposure -- TG Test Guideline -- UN GHS United Nations Globally Harmonized System of Classification and Labelling of Chemicals -- VITO Flemish Institute for Technological Research 1
- BAC benzalkonium chloride -- Cat 1 UN GHS classification for chemicals causing irreversible effects on the eye/serious damage to the eye -- Cat 2 UN GHS classification for chemicals causing reversible effects on the eye/eye irritation, sub-categorized in 2A (irritant to eyes, eye effects are not fully reversible within 7 days of observation) and 2B (mild irritant to eyes, eye effects fully reversible within 7 days of observation) -- CO corneal opacity -- Conj conjunctival redness (CR) and/or conjunctival chemosis (CC) -- CO pers. D21 CO persistence on day 21 -- CON4EI CONsortium for in vitro Eye Irritation testing strategy -- CP contact period -- CP1% 60-min CP with a 1% w/v concentration of the chemical -- CP10% 60-min CP with a 10% w/v concentration of the chemical -- CP3.5% 60-min CP with a 3.5% w/v concentration of the chemical -- DRD Draize eye test Reference Database -- FNR false negative rate -- FPR false positive rate -- IR iritis -- MP mucus production -- MP CP1% amount of mucus produced during CP1% -- MP CP10% amount of mucus produced during CP10% -- MP CP3.5% amount of mucus produced during CP3.5% -- NC negative control -- OECD Organization for Economic Co-operation and Development -- PC positive control -- pers persistence -- SMI Slug Mucosal Irritation -- TG Test Guideline -- UN GHS United Nations Globally Harmonized System of Classification and Labelling of Chemicals 1
- BCOP Bovine Corneal Opacity and Permeability -- BCOP LLBO Bovine Corneal Opacity and Permeability Laser Light based Opacitometer -- CAS RN Chemical Abstracts Service Registry Number -- Cat1 UN GHS classification for chemicals causing irreversible effects on the eye/serious damage to the eye -- Cat2 UN GHS classification for chemicals causing reversible effects on the eye/eye irritation, sub-categorised in 2A (irritant to eyes, eye effects are not fully reversible within 7 days of observation) and 2B (mild irritant to eyes, eye effects fully reversible within 7 days of observation) -- CO Corneal Opacity -- CON4EI CONsortium for in vitro Eye Irritation testing strategy -- EIT Eye Irritation Test -- EITL Eye Irritation Testing of Liquid/Viscous chemicals -- EITS Eye Irritation Testing of Solid chemicals -- EU CLP EU Classification, Labelling and Packaging regulation -- EURL ECVAM European Union Reference Laboratory for Alternatives to Animal Testing -- HCE Human Corneal Epithelium -- NC Negative control -- No Cat Chemicals not classified for serious eye damage/eye irritation under GHS/EU CLP -- No Pred No prediction can be made -- MTT 3-(4, 5-Dimethylthiazole-2-yl)-2, 5-diphenyltetrazolium bromide -- OD Optical density -- OECD Organisation for Economic Co-operation and Development -- PC Positive control -- PBS Phosphate-buffered saline -- pers Persistence -- RhCE Reconstructed human Cornea-like Epithelium -- SkinEthic™ HCE EIT SkinEthic™ Human Corneal Epithelium Eye Irritation Test -- SOP Standard operating procedure -- SMI Slug mucosal irritation -- TG Test Guideline -- UN GHS United Nations Globally Harmonized System of Classification and Labelling of Chemicals -- VITO Flemish Institute for Technological Research 1