1. The chemotherapeutic agent CX-5461 irreversibly blocks RNA polymerase I initiation and promoter release to cause nucleolar disruption, DNA damage and cell inviability. (6th November 2020) Authors: Mars, Jean-Clément; Tremblay, Michel G; Valere, Mélissa; Sibai, Dany S; Sabourin-Felix, Marianne; Lessard, Frédéric; Moss, Tom Journal: NAR cancer Issue: Volume 2:Number 4(2020) Page Start: Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗