1. Inhibition of catechol-O-methyltransferase in the cynomolgus monkey by opicapone after acute and repeated administration. (December 2018) Authors: Kitajima, Takashi; Mizote, Shintaro; Bonifácio, Maria João; Umemura, Takeo; Yoneda, Kazuhiro; Moser, Paul; Soares-da-Silva, Patrício; Tanaka, Makoto Journal: Neuropharmacology Issue: Volume 143(2018) Page Start: 282 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. Modeling and simulation of bone mineral density response from a phase 2 study of ONO‐5334, a new cathepsin K inhibitor, to support dose selection in osteoporosis. (28th February 2014) Authors: Hasegawa, Chihiro; Kastrissios, Helen; Monteleone, Jonathan; Ohno, Tomoya; Umemura, Takeo; Ohyama, Michiyo; Nagase, Shinichi; Small, Maria; Deacon, Steve; Ogawa, Mikio; Ieiri, Ichiro Journal: Journal of clinical pharmacology Issue: Volume 54:Number 8(2014:Aug.) Page Start: 937 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
3. Population pharmacokinetic and pharmacodynamic modeling of different formulations of ONO‐5334, cathepsin K inhibitor, in Caucasian and Japanese postmenopausal females. (10th October 2013) Authors: Hasegawa, Chihiro; Ohno, Tomoya; Umemura, Takeo; Honda, Naoki; Ohyama, Michiyo; Nagase, Shinichi; Small, Maria; Deacon, Steve; Ogawa, Mikio; Ieiri, Ichiro Journal: Journal of clinical pharmacology Issue: Volume 54:Number 1(2014:Jan.) Page Start: 23 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗