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Author/Creator Trapa, Patrick

1. [O2–17–04]: PHARMACOKINETIC/PHARMACODYNAMIC (PK/PD) EFFECTS OF PF‐06648671, A NOVEL GAMMA SECRETASE MODULATOR (GSM), FOLLOWING SINGLE AND MULTIPLE DOSE ADMINISTRATION IN HEALTHY VOLUNTEERS. (1st July 2017)

Authors:
Ahn, Jae Eun; Liu, Richann; Trapa, Patrick; Wood, Kathleen M.; Hajos‐Korcsok, Eva; Fullerton, Terence; Qiu, Ruolun
Journal:
Alzheimer's & dementia
Issue:
Volume 13:Supplement 7S(2017)Part 12
Page Start:
P601
Record Type:
Journal Article
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2. Discovery of a Highly Selective Glycogen Synthase Kinase‐3 Inhibitor (PF‐04802367) That Modulates Tau Phosphorylation in the Brain: Translation for PET Neuroimaging. (29th June 2016)

Authors:
Liang, Steven H.; Chen, Jinshan Michael; Normandin, Marc D.; Chang, Jeanne S.; Chang, George C.; Taylor, Christine K.; Trapa, Patrick; Plummer, Mark S.; Para, Kimberly S.; Conn, Edward L.; Lopresti‐Morrow, Lori; Lanyon, Lorraine F.; Cook, James M.; Richter, Karl E. G.; Nolan, Charlie E.; Schachte...
Journal:
Angewandte Chemie
Issue:
Volume 128:Number 33(2016)
Page Start:
9753
Record Type:
Journal Article
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3. Discovery of a Highly Selective Glycogen Synthase Kinase‐3 Inhibitor (PF‐04802367) That Modulates Tau Phosphorylation in the Brain: Translation for PET Neuroimaging. Issue 33 (29th June 2016)

Authors:
Liang, Steven H.; Chen, Jinshan Michael; Normandin, Marc D.; Chang, Jeanne S.; Chang, George C.; Taylor, Christine K.; Trapa, Patrick; Plummer, Mark S.; Para, Kimberly S.; Conn, Edward L.; Lopresti‐Morrow, Lori; Lanyon, Lorraine F.; Cook, James M.; Richter, Karl E. G.; Nolan, Charlie E.; Schachte...
Journal:
Angewandte Chemie international edition
Issue:
Volume 55:Issue 33(2016)
Page Start:
9601
Record Type:
Journal Article
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4. Next‐generation Bruton's tyrosine kinase inhibitor BIIB091 selectively and potently inhibits B cell and Fc receptor signaling and downstream functions in B cells and myeloid cells. Issue 6 (14th June 2021)

Authors:
Bame, Eris; Tang, Hao; Burns, Jeremy C; Arefayene, Million; Michelsen, Klaus; Ma, Bin; Marx, Isaac; Prince, Robin; Roach, Allie M; Poreci, Urjana; Donaldson, Douglas; Cullen, Patrick; Casey, Fergal; Zhu, Jing; Carlile, Thomas M; Sangurdekar, Dipen; Zhang, Baohong; Trapa, Patrick; Santoro, Joseph;...
Journal:
Clinical & translational immunology
Issue:
Volume 10:Issue 6(2021)
Page Start:
n/a
Record Type:
Journal Article
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5. Optimization of dose and route of administration of the P‐glycoprotein inhibitor, valspodar (PSC‐833) and the P‐glycoprotein and breast cancer resistance protein dual‐inhibitor, elacridar (GF120918) as dual infusion in rats. Issue 2 (4th March 2021)

Authors:
Rowbottom, Christopher; Pietrasiewicz, Alicia; Tuczewycz, Taras; Grater, Richard; Qiu, Daniel; Kapadnis, Sudarshan; Trapa, Patrick
Journal:
Pharmacology research & perspectives
Issue:
Volume 9:Issue 2(2021)
Page Start:
n/a
Record Type:
Journal Article
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6. P4–298: Understanding the target and evaluating the consequences of gamma‐secretase modulation from in vitro models to higher‐order species. (1st July 2013)

Authors:
Wood, Kathleen; Pozdnyakov, Nikolay; Sylvain, Emily; Marconi, Michael; Robshaw, Ashley; Pustilnik, Leslie; Steyn, Stefanus; Trapa, Patrick; Lu, Yasong; Johnson, Douglas; Pettersson, Martin; Bales, Kelly
Journal:
Alzheimer's & dementia
Issue:
Volume 9:Supplement 4S(2013)Part 20
Page Start:
P814
Record Type:
Journal Article
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7. Translational pharmacokinetic-pharmacodynamic analysis in the pharmaceutical industry: an IQ Consortium PK-PD Discussion Group perspective. Issue 10 (October 2017)

Authors:
Wong, Harvey; Bohnert, Tonika; Damian-Iordache, Valeriu; Gibson, Christopher; Hsu, Cheng-Pang; Krishnatry, Anu Shilpa; Liederer, Bianca M.; Lin, Jing; Lu, Qiang; Mettetal, Jerome T.; Mudra, Daniel R.; Nijsen, Marjoleen J.M.A.; Schroeder, Patricia; Schuck, Edgar; Suryawanshi, Satyendra; Trapa, Pat...
Journal:
Drug discovery today
Issue:
Volume 22:Issue 10(2017)
Page Start:
1447
Record Type:
Journal Article
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