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- Tomimoto, Masaki [remove] 4
- 615.19 4
- Biochemistry -- Periodicals 4
- Bioorganic chemistry -- Periodicals 4
- Chemistry, Clinical -- Periodicals 4
- Chemistry, Organic -- Periodicals 4
- Chimie bio-organique -- Périodiques 4
- Chimie pharmaceutique -- Périodiques 4
- Pharmaceutical chemistry -- Periodicals 4
- AcOH acetic acid -- Ang I angiotensin I -- Ang II angiotensin II -- AUC area under the blood concentration–time curve -- C5min concentration in plasma 5 min after administration -- CLtotal total clearance -- Cmax maximum concentration in plasma -- DIEA N, N-diisopropylethylamine -- Et3N triethylamine -- EtOAc ethyl acetate -- EtOH ethanol -- F rat bioavailability -- HAC heavy atom count -- HOBt 1-hydroxybenzotriazole hydrate -- hPRA human plasma renin activity -- i-PrOH isopropanol -- LE ligand efficiency -- MeOH methanol -- MRT mean residence time -- Pd/C palladium on carbon -- RAAS renin-angiotensin-aldosterone system -- Rt retention time -- Vd(ss) volume of distribution at steady state -- WSC (1-[3-(dimethylamino)propyl]-3-ethylcarbodiimide 2
- Fragment-based drug discovery (FBDD) -- High-throughput synthetic chemistry -- Structure-based drug design (SBDD) -- Renin inhibitor -- Crystal structure 2