1. A Quantitative Systems Pharmacology Model of Gaucher Disease Type 1 Provides Mechanistic Insight Into the Response to Substrate Reduction Therapy With Eliglustat. (19th June 2020) Authors: Abrams, Ruth; Kaddi, Chanchala D.; Tao, Mengdi; Leiser, Randolph J.; Simoni, Giulia; Reali, Federico; Tolsma, John; Jasper, Paul; van Rijn, Zachary; Li, Jing; Niesner, Bradley; Barrett, Jeffrey S.; Marchetti, Luca; Peterschmitt, M. Judith; Azer, Karim; Neves‐Zaph, Susana Journal: CPT: pharmacometrics & systems pharmacology Issue: Volume 9:Number 7(2020) Page Start: 374 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. Quantitative Systems Pharmacology Modeling of Acid Sphingomyelinase Deficiency and the Enzyme Replacement Therapy Olipudase Alfa Is an Innovative Tool for Linking Pathophysiology and Pharmacology. (19th June 2018) Authors: Kaddi, Chanchala D.; Niesner, Bradley; Baek, Rena; Jasper, Paul; Pappas, John; Tolsma, John; Li, Jing; van Rijn, Zachary; Tao, Mengdi; Ortemann‐Renon, Catherine; Easton, Rachael; Tan, Sharon; Puga, Ana Cristina; Schuchman, Edward H.; Barrett, Jeffrey S.; Azer, Karim Journal: CPT: pharmacometrics & systems pharmacology Issue: Volume 7:Number 7(2018) Page Start: 442 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗