1. DNA Damage Response (DDR) Basket of Baskets (D-BOB) Trial: Phase 1/2 Study of the ATR inhibitor (ATRi) berzosertib and PD-L1 inhibitor avelumab in patients (pts) with advanced solid tumors with DDR molecular alterations. (October 2022) Authors: Ngoi, N.; Pilie, P.G.; Piha-Paul, S.A.; Dumbrava, E.E.; Fu, S.; Hong, D.S.; Karp, D.D.; Naing, A.; Pant, S.; Rodon Ahnert, J.; Subbiah, V.; Tsimberidou, A.M.; Salguero, C.; Brown, C.V.; Hoadley, W.E.; Johnson, A.; Yuan, Y.; Westin, S.N.; Meric-Bernstam, F.; Yap, T.A. Journal: European journal of cancer Issue: Volume 174(2022)Supplement 1 Page Start: S10 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. Identifying FGFR2 fusions/rearrangements in cholangiocarcinoma patients using a novel cfDNA algorithm for treatment with RLY-4008, a highly selective irreversible FGFR2 inhibitor. (October 2022) Authors: Schram, A.; Borad, M.; Sahai, V.; Kamath, S.; Kim, R.; Liao, C.Y.A.; Oh, D.Y.; Ponz-Sarvisé, M.; Yachnin, J.; Shell, S.A.; Cassier, P.; Dotan, E.; Florou, V.; Moreno, V.; Park, J.O.; Tai, D.; Schmidt-Kittler, O.; Ferté, C.; Goyal, L.; Subbiah, V. Journal: European journal of cancer Issue: Volume 174(2022)Supplement 1 Page Start: S116 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
3. NCI10329: Phase Ib Sequential Trial of Agents against DNA Repair (STAR) Study to investigate the sequential combination of the Poly (ADP-Ribose) Polymerase inhibitor (PARPi) olaparib (ola) and WEE1 inhibitor (WEE1i) adavosertib (ada) in patients (pts) with DNA Damage Response (DDR)-aberrant advanced tumors, enriched for BRCA1/2 mutated and CCNE1 amplified cancers. (October 2022) Authors: Yap, T.A.; Ngoi, N.; Dumbrava, E.E.; Karp, D.D.; Rodon Ahnert, J.; Fu, S.; Hong, D.S.; Naing, A.; Pant, S.; Piha-Paul, S.A.; Subbiah, V.; Tsimberidou, A.M.; Dufner, D.; Rhudy, J.; Gore, S.; Ivy, S.P.; Yuan, Y.; Westin, S.N.; Mills, G.B.; Meric-Bernstam, F. Journal: European journal of cancer Issue: Volume 174(2022)Supplement 1 Page Start: S7 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗